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raer

This is the development version of raer; for the stable release version, see raer.

RNA editing tools in R


Bioconductor version: Development (3.24)

Toolkit for identification and statistical testing of RNA editing signals from within R. Provides support for identifying sites from bulk-RNA and single cell RNA-seq datasets, and general methods for extraction of allelic read counts from alignment files. Facilitates annotation and exploratory analysis of editing signals using Bioconductor packages and resources.

Author: Kent Riemondy [aut, cre] ORCID iD ORCID: 0000-0003-0750-1273 , Kristen Wells-Wrasman [aut] ORCID iD ORCID: 0000-0002-7466-8164 , Ryan Sheridan [ctb] ORCID iD ORCID: 0000-0003-4012-3147 , Jay Hesselberth [ctb] ORCID iD ORCID: 0000-0002-6299-179X , RNA Bioscience Initiative [cph, fnd]

Maintainer: Kent Riemondy <kent.riemondy at gmail.com>

Citation (from within R, enter citation("raer")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("raer")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("raer")
Introduction HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Alignment, Annotation, Coverage, Epitranscriptomics, FeatureExtraction, MultipleComparison, RNASeq, Sequencing, SingleCell, Software
Version 1.11.1
In Bioconductor since BioC 3.18 (R-4.3) (3 years)
License MIT + file LICENSE
Depends
Imports stats, methods, GenomicRanges, IRanges, Rsamtools, BSgenome, Biostrings, SummarizedExperiment, SingleCellExperiment, S4Vectors, Seqinfo, GenomeInfoDb, GenomicAlignments, GenomicFeatures, BiocGenerics, BiocParallel, rtracklayer, Matrix, cli
System Requirements GNU make
URL https://rnabioco.github.io/raer https://github.com/rnabioco/raer
Bug Reports https://github.com/rnabioco/raer/issues
See More
Suggests testthat (>= 3.0.0), knitr, DESeq2, edgeR, limma, rmarkdown, BiocStyle, ComplexHeatmap, TxDb.Hsapiens.UCSC.hg38.knownGene, SNPlocs.Hsapiens.dbSNP144.GRCh38, BSgenome.Hsapiens.NCBI.GRCh38, scater, scran, scuttle, AnnotationHub, covr, raerdata, txdbmaker
Linking To Rhtslib
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package raer_1.11.1.tar.gz
Windows Binary (x86_64) raer_1.11.1.zip
macOS Binary (big-sur-x86_64) raer_1.11.1.tgz
macOS Binary (sonoma-arm64) raer_1.11.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/raer
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/raer
Bioc Package Browser https://code.bioconductor.org/browse/raer/
Package Short Url https://bioconductor.org/packages/raer/
Package Downloads Report Download Stats