Registration Open for Bioc2024 July 24-26


Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping

Bioconductor version: Release (3.19)

This package contains the experimental data and a complete executable transcript (vignette) of the analysis of the HCT116 genetic interaction matrix presented in the paper "Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping" by C. Laufer, B. Fischer, M. Billmann, W. Huber, M. Boutros; Nature Methods (2013) 10:427-31. doi: 10.1038/nmeth.2436.

Author: Bernd Fischer

Maintainer: Mike Smith <mike.smith at>

Citation (from within R, enter citation("HD2013SGI")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

HD2013SGI PDF R Script
Reference Manual PDF


biocViews CancerData, CellCulture, ColonCancerData, ExperimentData, HighThroughputImagingData, Homo_sapiens_Data, MicrotitrePlateAssayData
Version 1.44.0
License Artistic-2.0
Depends R (>= 2.10.0), RColorBrewer, gplots, geneplotter, splots, limma, vcd, LSD, EBImage
System Requirements GNU make
See More
Suggests BiocStyle
Linking To
Depends On Me
Imports Me
Suggests Me splots
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HD2013SGI_1.44.0.tar.gz
Windows Binary
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone
Source Repository (Developer Access) git clone
Package Short Url
Package Downloads Report Download Stats