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Estimate the cell composition of whole blood in DNA methylation samples

Bioconductor version: Release (3.19)

A tool to estimate the cell composition of DNA methylation whole blood sample measured on any platform technology (microarray and sequencing).

Author: Stephanie C. Hicks [aut, cre] , Rafael Irizarry [aut]

Maintainer: Stephanie C. Hicks <shicks19 at>

Citation (from within R, enter citation("methylCC")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

The methylCC user's guide HTML R Script
Reference Manual PDF


biocViews DNAMethylation, MethylSeq, MethylationArray, Microarray, Sequencing, Software, WholeGenome
Version 1.18.0
In Bioconductor since BioC 3.10 (R-3.6) (4.5 years)
License GPL-3
Depends R (>= 3.6), FlowSorted.Blood.450k
Imports Biobase, GenomicRanges, IRanges, S4Vectors, dplyr, magrittr, minfi, bsseq, quadprog, plyranges, stats, utils, bumphunter, genefilter, methods, IlluminaHumanMethylation450kmanifest, IlluminaHumanMethylation450kanno.ilmn12.hg19
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Suggests rmarkdown, knitr, testthat (>= 2.1.0), BiocGenerics, BiocStyle, tidyr, ggplot2
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Follow Installation instructions to use this package in your R session.

Source Package methylCC_1.18.0.tar.gz
Windows Binary
macOS Binary (x86_64) methylCC_1.18.0.tgz
macOS Binary (arm64) methylCC_1.18.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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