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This is the development version of topGO; for the stable release version, see topGO.

Enrichment Analysis for Gene Ontology

Bioconductor version: Development (3.20)

topGO package provides tools for testing GO terms while accounting for the topology of the GO graph. Different test statistics and different methods for eliminating local similarities and dependencies between GO terms can be implemented and applied.

Author: Adrian Alexa, Jorg Rahnenfuhrer

Maintainer: Adrian Alexa <adrian.alexa at>

Citation (from within R, enter citation("topGO")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

topGO PDF R Script
Reference Manual PDF


biocViews Microarray, Software, Visualization
Version 2.57.0
In Bioconductor since BioC 2.0 (R-2.5) (17 years)
License LGPL
Depends R (>= 2.10.0), methods, BiocGenerics(>= 0.13.6), graph(>= 1.14.0), Biobase(>= 2.0.0), GO.db(>= 2.3.0), AnnotationDbi(>= 1.7.19), SparseM (>= 0.73)
Imports lattice, matrixStats, DBI
System Requirements
See More
Suggests ALL, hgu95av2.db, hgu133a.db, genefilter, xtable, multtest, Rgraphviz, globaltest
Linking To
Depends On Me BgeeDB, compEpiTools, EGSEA, ideal, moanin, tRanslatome, maEndToEnd
Imports Me APL, cellity, consICA, GRaNIE, mosdef, OmaDB, pcaExplorer, psygenet2r, transcriptogramer, ViSEAGO, ExpHunterSuite
Suggests Me fenr, FGNet, GeDi, geva, IntramiRExploreR, miRNAtap, pareg
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package topGO_2.57.0.tar.gz
Windows Binary
macOS Binary (x86_64) topGO_2.57.0.tgz
macOS Binary (arm64) topGO_2.57.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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