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escape

This is the development version of escape; for the stable release version, see escape.

Easy single cell analysis platform for enrichment


Bioconductor version: Development (3.22)

A bridging R package to facilitate gene set enrichment analysis (GSEA) in the context of single-cell RNA sequencing. Using raw count information, Seurat objects, or SingleCellExperiment format, users can perform and visualize ssGSEA, GSVA, AUCell, and UCell-based enrichment calculations across individual cells. Alternatively, escape supports use of rank-based GSEA, such as the use of differential gene expression via fgsea.

Author: Nick Borcherding [aut, cre], Jared Andrews [aut], Alexei Martsinkovskiy [ctb]

Maintainer: Nick Borcherding <ncborch at gmail.com>

Citation (from within R, enter citation("escape")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("escape")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("escape")
Escape-ingToWork HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Annotation, Classification, GeneSetEnrichment, GeneSignaling, Pathways, Sequencing, SingleCell, Software
Version 2.5.3
In Bioconductor since BioC 3.12 (R-4.0) (4.5 years)
License MIT + file LICENSE
Depends R (>= 4.1)
Imports ggdist, ggplot2 (>= 3.5.0), grDevices, Matrix, MatrixGenerics, methods, stats, SummarizedExperiment, utils
System Requirements
URL
Bug Reports https://github.com/BorchLab/escape/issues
See More
Suggests AUCell, BiocParallel, BiocStyle, dplyr, fgsea, GSEABase, ggraph, ggridges, ggpointdensity, GSVA, hexbin, igraph, irlba, knitr, msigdb, patchwork, rmarkdown, rlang, scran, SeuratObject, Seurat, SingleCellExperiment, spelling, stringr, testthat (>= 3.0.0), UCell
Linking To
Enhances
Depends On Me
Imports Me
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Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package escape_2.5.3.tar.gz
Windows Binary (x86_64) escape_2.5.3.zip
macOS Binary (x86_64) escape_2.5.3.tgz
macOS Binary (arm64) escape_2.5.3.tgz
Source Repository git clone https://git.bioconductor.org/packages/escape
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/escape
Bioc Package Browser https://code.bioconductor.org/browse/escape/
Package Short Url https://bioconductor.org/packages/escape/
Package Downloads Report Download Stats