Bioconductor 3.22 Released

SmartPhos

This is the development version of SmartPhos; for the stable release version, see SmartPhos.

A phosphoproteomics data analysis package with an interactive ShinyApp


Bioconductor version: Development (3.23)

To facilitate and streamline phosphoproteomics data analysis, we developed SmartPhos, an R package for the pre-processing, quality control, and exploratory analysis of phosphoproteomics data generated by MaxQuant and Spectronaut. The package can be used either through the R command line or through an interactive ShinyApp called SmartPhos Explorer. The package contains methods such as normalization and normalization correction, transformation, imputation, batch effect correction, PCA, heatmap, differential expression, time-series clustering, gene set enrichment analysis, and kinase activity inference.

Author: Shubham Agrawal [aut, cre] ORCID iD ORCID: 0009-0005-2630-9342 , Junyan Lu [aut] ORCID iD ORCID: 0000-0002-9211-0746

Maintainer: Shubham Agrawal <shubhamagrawal2706 at gmail.com>

Citation (from within R, enter citation("SmartPhos")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("SmartPhos")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews BatchEffect, Clustering, DifferentialExpression, GUI, GeneExpression, GeneSetEnrichment, MassSpectrometry, Normalization, Preprocessing, Proteomics, QualityControl, ShinyApps, Software, Visualization
Version 1.1.0
In Bioconductor since BioC 3.22 (R-4.5) (< 6 months)
License GPL-3
Depends R (>= 4.4.0)
Imports MultiAssayExperiment, SummarizedExperiment, data.table, shiny, shinythemes, shinyjs, shinyBS, shinyWidgets, parallel, DT, tools, stats, ggplot2, plotly, ggbeeswarm, pheatmap, grid, XML, MsCoreUtils, imputeLCMD, missForest, limma, proDA, decoupleR, piano, BiocParallel, doParallel, doRNG, e1071, magrittr, matrixStats, rlang, stringr, tibble, dplyr, tidyr, Biobase, vsn, factoextra, cowplot
System Requirements
URL https://lu-group-ukhd.github.io/SmartPhos/
Bug Reports https://github.com/Bioconductor/SmartPhos/issues
See More
Suggests knitr, BiocStyle, PhosR, testthat
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/SmartPhos
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/SmartPhos
Package Short Url https://bioconductor.org/packages/SmartPhos/
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