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This is the development version of CGHnormaliter; for the stable release version, see CGHnormaliter.

Normalization of array CGH data with imbalanced aberrations.

Bioconductor version: Development (3.20)

Normalization and centralization of array comparative genomic hybridization (aCGH) data. The algorithm uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs).

Author: Bart P.P. van Houte, Thomas W. Binsl, Hannes Hettling

Maintainer: Bart P.P. van Houte <bvhoute at>

Citation (from within R, enter citation("CGHnormaliter")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

CGHnormaliter PDF R Script
Reference Manual PDF


biocViews Microarray, Preprocessing, Software
Version 1.59.0
In Bioconductor since BioC 2.5 (R-2.10) (14.5 years)
License GPL (>= 3)
Depends CGHcall(>= 2.17.0), CGHbase(>= 1.15.0)
Imports Biobase, CGHbase, CGHcall, methods, stats, utils
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