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spqn

This is the released version of spqn; for the devel version, see spqn.

Spatial quantile normalization


Bioconductor version: Release (3.23)

The spqn package implements spatial quantile normalization (SpQN). This method was developed to remove a mean-correlation relationship in correlation matrices built from gene expression data. It can serve as pre-processing step prior to a co-expression analysis.

Author: Yi Wang [cre, aut], Kasper Daniel Hansen [aut]

Maintainer: Yi Wang <yiwangthu5 at gmail.com>

Citation (from within R, enter citation("spqn")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("spqn")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("spqn")
spqn User's Guide HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews GraphAndNetwork, NetworkInference, Normalization, Software
Version 1.24.0
In Bioconductor since BioC 3.11 (R-4.0) (6.5 years)
License Artistic-2.0
Depends R (>= 4.0), ggplot2, ggridges, SummarizedExperiment, BiocGenerics
Imports graphics, stats, utils, matrixStats
System Requirements
URL https://github.com/hansenlab/spqn
Bug Reports https://github.com/hansenlab/spqn/issues
See More
Suggests BiocStyle, knitr, rmarkdown, tools, spqnData(>= 0.99.3), RUnit
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package spqn_1.24.0.tar.gz
Windows Binary (x86_64) spqn_1.24.0.zip
macOS Binary (big-sur-x86_64) spqn_1.24.0.tgz
macOS Binary (sonoma-arm64) spqn_1.24.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/spqn
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/spqn
Bioc Package Browser https://code.bioconductor.org/browse/spqn/
Package Short Url https://bioconductor.org/packages/spqn/
Package Downloads Report Download Stats