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Functions to perform cancer outlier profile analysis.

Bioconductor version: Release (3.19)

COPA is a method to find genes that undergo recurrent fusion in a given cancer type by finding pairs of genes that have mutually exclusive outlier profiles.

Author: James W. MacDonald

Maintainer: James W. MacDonald <jmacdon at>

Citation (from within R, enter citation("copa")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

copa Overview PDF R Script
Reference Manual PDF


biocViews DifferentialExpression, OneChannel, Software, TwoChannel, Visualization
Version 1.72.0
In Bioconductor since BioC 1.8 (R-2.3) (18 years)
License Artistic-2.0
Depends Biobase, methods
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Follow Installation instructions to use this package in your R session.

Source Package copa_1.72.0.tar.gz
Windows Binary
macOS Binary (x86_64) copa_1.72.0.tgz
macOS Binary (arm64) copa_1.72.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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