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Reactome Pathway Analysis

Bioconductor version: Release (3.19)

This package provides functions for pathway analysis based on REACTOME pathway database. It implements enrichment analysis, gene set enrichment analysis and several functions for visualization. This package is not affiliated with the Reactome team.

Author: Guangchuang Yu [aut, cre], Vladislav Petyuk [ctb]

Maintainer: Guangchuang Yu <guangchuangyu at>

Citation (from within R, enter citation("ReactomePA")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

An R package for Reactome Pathway Analysis HTML R Script
Reference Manual PDF


biocViews Annotation, GeneSetEnrichment, MultipleComparison, Pathways, Reactome, Software, Visualization
Version 1.48.0
In Bioconductor since BioC 2.10 (R-2.15) (12 years)
License GPL-2
Depends R (>= 3.4.0)
Imports AnnotationDbi, DOSE(>= 3.5.1), enrichplot, ggplot2 (>= 3.3.5), ggraph, reactome.db, igraph, graphite, gson
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Suggests BiocStyle, clusterProfiler, knitr, rmarkdown,, prettydoc, testthat
Linking To
Depends On Me maEndToEnd
Imports Me Pigengene, bioCancer, gINTomics, miRSM, scTensor, ExpHunterSuite
Suggests Me CBNplot, CINdex, ChIPseeker, GRaNIE, GeDi, cola, scGPS
Links To Me
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Follow Installation instructions to use this package in your R session.

Source Package ReactomePA_1.48.0.tar.gz
Windows Binary
macOS Binary (x86_64) ReactomePA_1.48.0.tgz
macOS Binary (arm64) ReactomePA_1.48.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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