MSstatsResponse
This is the released version of MSstatsResponse; for the devel version, see MSstatsResponse.
Statistical Methods for Chemoproteomics Dose-Response Analysis
Bioconductor version: Release (3.23)
Tools for detecting drug-protein interactions and estimating IC50 values from chemoproteomics data. Implements semi-parametric isotonic regression, bootstrapping, and curve fitting to evaluate compound effects on protein abundance.
Author: Sarah Szvetecz [aut, cre], Tony Wu [aut], Devon Kohler [aut], Olga Vitek [aut]
Maintainer: Sarah Szvetecz <szvetecz.s at northeastern.edu>
citation("MSstatsResponse")):
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("MSstatsResponse")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("MSstatsResponse")| MSstatsResponse User Guide | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | MassSpectrometry, Proteomics, Regression, Software, StatisticalMethod |
| Version | 1.2.0 |
| In Bioconductor since | BioC 3.22 (R-4.5) (1 year) |
| License | Artistic-2.0 |
| Depends | R (>= 4.5.0) |
| Imports | BiocParallel, ggplot2, dplyr, stats, parallel, data.table, tidyr, stringr, plotly, utils |
| System Requirements | |
| URL | https://github.com/Vitek-Lab/MSstatsResponse |
| Bug Reports | https://github.com/Vitek-Lab/MSstatsResponse/issues |
See More
| Suggests | MSstats, MSstatsTMT, tidyverse, boot, purrr, gridExtra, knitr, rmarkdown, BiocStyle, testthat |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | MSstatsShiny |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | MSstatsResponse_1.2.0.tar.gz |
| Windows Binary (x86_64) | |
| macOS Binary (big-sur-x86_64) | MSstatsResponse_1.2.0.tgz |
| macOS Binary (sonoma-arm64) | MSstatsResponse_1.2.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/MSstatsResponse |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/MSstatsResponse |
| Bioc Package Browser | https://code.bioconductor.org/browse/MSstatsResponse/ |
| Package Short Url | https://bioconductor.org/packages/MSstatsResponse/ |
| Package Downloads Report | Download Stats |