MMDiff2
This is the released version of MMDiff2; for the devel version, see MMDiff2.
Statistical Testing for ChIP-Seq data sets
Bioconductor version: Release (3.23)
This package detects statistically significant differences between read enrichment profiles in different ChIP-Seq samples. To take advantage of shape differences it uses Kernel methods (Maximum Mean Discrepancy, MMD).
Author: Gabriele Schweikert [cre, aut], David Kuo [aut]
Maintainer: Gabriele Schweikert <gschweik at staffmail.ed.ac.uk>
citation("MMDiff2")):
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("MMDiff2")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("MMDiff2")| An Introduction to the MMDiff2 method | R Script | |
| Reference Manual |
Details
| biocViews | ChIPSeq, DifferentialPeakCalling, Sequencing, Software |
| Version | 1.40.0 |
| In Bioconductor since | BioC 3.3 (R-3.3) (10.5 years) |
| License | Artistic-2.0 |
| Depends | R (>= 3.5.0), Rsamtools, Biobase |
| Imports | GenomicRanges, locfit, BSgenome, Biostrings, shiny, ggplot2, RColorBrewer, graphics, grDevices, parallel, S4Vectors, methods |
| System Requirements | |
| URL |
See More
| Suggests | MMDiffBamSubset, MotifDb, knitr, BiocStyle, BSgenome.Mmusculus.UCSC.mm9 |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | MMDiffBamSubset |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | MMDiff2_1.40.0.tar.gz |
| Windows Binary (x86_64) | MMDiff2_1.40.0.zip |
| macOS Binary (big-sur-x86_64) | MMDiff2_1.40.0.tgz |
| macOS Binary (sonoma-arm64) | MMDiff2_1.40.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/MMDiff2 |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/MMDiff2 |
| Bioc Package Browser | https://code.bioconductor.org/browse/MMDiff2/ |
| Package Short Url | https://bioconductor.org/packages/MMDiff2/ |
| Package Downloads Report | Download Stats |