Package: SimBu
Title: Simulate Bulk RNA-seq Datasets from Single-Cell Datasets
Version: 1.12.0
Authors@R: 
    person(given = "Alexander",
           family = "Dietrich",
           role = c("aut", "cre"),
           email = "alex.dietrich@tum.de")
Description: SimBu can be used to simulate bulk RNA-seq datasets with known cell type fractions. 
    You can either use your own single-cell study for the simulation or the sfaira database. 
    Different pre-defined simulation scenarios exist, as are options to run custom simulations.
    Additionally, expression values can be adapted by adding an mRNA bias, which produces more
    biologically relevant simulations.
License: GPL-3 + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Imports: basilisk, BiocParallel, data.table, dplyr, ggplot2, tools,
        Matrix (>= 1.3.3), methods, phyloseq, proxyC, RColorBrewer,
        RCurl, reticulate, sparseMatrixStats, SummarizedExperiment,
        tidyr
Suggests: curl, knitr, matrixStats, rmarkdown, Seurat (>= 5.0.0),
        SeuratObject (>= 5.0.0), testthat (>= 3.0.0)
URL: https://github.com/omnideconv/SimBu
BugReports: https://github.com/omnideconv/SimBu/issues
VignetteBuilder: knitr
Config/testthat/edition: 3
StagedInstall: no
biocViews: Software, RNASeq, SingleCell
git_url: https://git.bioconductor.org/packages/SimBu
git_branch: RELEASE_3_22
git_last_commit: c0333a2
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.22
Date/Publication: 2025-10-29
NeedsCompilation: no
Packaged: 2025-10-30 05:28:32 UTC; biocbuild
Author: Alexander Dietrich [aut, cre]
Maintainer: Alexander Dietrich <alex.dietrich@tum.de>
Built: R 4.5.1; ; 2025-10-30 12:40:13 UTC; unix
