compound_name	synonyms	species	strain	dosage	avg_lifespan_change	max_lifespan_change	gender	significance	pubmed_id	Comment	pref_name	chembl_id	pubchem_cid	DrugBank_id
Vitexin	NA	Caenorhabditis elegans	N2	50 µM	8	5.3	NA	NA	26535084	NA	VITEXIN	CHEMBL487417	5280441	NA
Cyclosporin A	NA	Caenorhabditis elegans	NA	88 µM	18	NA	NA	NA	24134630	NA	NA	CHEMBL160	NA	DB00091
Histidine	L-histidine	Caenorhabditis elegans	N2	5 mM	10	NA	NA	NA	25643626	NA	HISTIDINE	CHEMBL17962	6274, 6971009	DB00117
SRT1720	NA	Mus musculus	C57BL/6J	100 mg/kg body weight	8.8	0	NA	NA	24582957	NA	NA	CHEMBL257991	NA	NA
Cordyceps sinensis oral liquid	NA	Drosophila melanogaster	Oregon-K	0.20 mg/ml	32	15.4	Male	NA	26239097	Mix	NA	NA	NA	NA
Lysine	NA	Caenorhabditis elegans	N2	5 mM	8	NA	NA	NA	25643626	NA	LYSINE	CHEMBL8085	5962, 122198194	DB00123, DB11101
Kinetin	NA	Zaprionus paravittiger	NA	3125 ppm	-71	-47.1	Male	NA	7488181	NA	KINETIN	CHEMBL228792	3830	DB11336
Arginine	NA	Caenorhabditis elegans	N2	1 mM	8	NA	NA	NA	25643626	NA	ARGININE	CHEMBL1485	28782, 6322	DB00125
Leucine	NA	Caenorhabditis elegans	N2	1 mM	16	NA	NA	NA	25643626	NA	LEUCINE	CHEMBL291962	7045798, 6106	DB00149
Rapamycin	NA	Mus musculus	Hybrid of CB6F1(F)& C3D2F1(M)	2.24 mg/kg/day	13	14	Female	NA	19587680	NA	NA	CHEMBL413	NA	DB00877, DB02439
Ascorbic Acid	Vitamin C	Caenorhabditis elegans	N2	80 µg/ml	0	NA	NA	NA	3374177	NA	ASCORBIC ACID	CHEMBL196	54670067	DB00126, DB11167, DB11316, DB11170, DB09541, DB11317
Ascorbic acid	Vitamin C	Paramecium tetraurelia	NA	50 mg/L	12.1	6.7	NA	NA	9406982	NA	ASCORBIC ACID	CHEMBL196	54670067	DB00126, DB11167, DB11316, DB11170, DB09541, DB11317
Ciclopirox olamine	NA	Caenorhabditis elegans	N2	0.0001	41	52	NA	NA	22114686	Mix	NA	NA	NA	NA
Spermine	SPM	Mus musculus	Crj:CD-1	3 mg.kg-1.dose-1	NA	NA	Female	NA	21858192	NA	SPERMINE	CHEMBL23194	1103	DB00127, DB02564
Ethoxyquin	NA	Mus musculus	C3H	0.5% w/w	18.1	NA	Male	NA	4927196	NA	NA	CHEMBL172064	3293	NA
Ornithine	NA	Caenorhabditis elegans	N2	100 µM	3	NA	NA	NS	25643626	NA	ORNITHINE	CHEMBL446143	6262, 88747248	DB00129
Glutamine	NA	Caenorhabditis elegans	N2	1 mM	15	NA	NA	NA	25643626	NA	GLUTAMINE	CHEMBL930	6992086, 5961	DB00130
Dihydroergotamine methanesulfonate	NA	Caenorhabditis elegans	NA	88 µM	24	NA	NA	NA	24134630	NA	NA	CHEMBL1200517	NA	DB00320, DB05743
(S)-2-hydroxyglutarate	NA	Caenorhabditis elegans	NA	8 mM	31.8	NA	NA	NA	26190651	NA	NA	CHEMBL1615211	NA	NA
Serine	L-serine	Caenorhabditis elegans	N2	10 mM	9	NA	NA	NA	25643626	NA	SERINE	CHEMBL11298	6857581, 5951	DB00133, DB03375
Sulfamethoxazole	SMX	Caenorhabditis elegans	N2	400 µM	18	0	NA	NA	24034891	NA	SULFAMETHOXAZOLE	CHEMBL443	5329	DB01015
Methionine	NA	Caenorhabditis elegans	N2	5 mM	8	NA	NA	NA	25643626	NA	METHIONINE	CHEMBL42336	6137, 6992087	DB00134
Tyrosine	NA	Caenorhabditis elegans	N2	10 mM	2	NA	NA	NS	25643626	NA	TYROSINE	CHEMBL925	6942100, 6057	DB00135
Jania acutilobum extract	Red Algae extract	Brachionus manjavacas	NA	5 µg/ml	9.1	NA	NA	NA	24120568	Mix	NA	NA	NA	NA
Lutein	NA	Drosophila melanogaster	NA	0.1 mg/ml	11.4	NA	NA	NA	23993264	NA	LUTEIN	CHEMBL173929	5281243	DB00137, DB11138
SU 4312	NA	Caenorhabditis elegans	NA	88µM	5	NA	NA	NA	24134630	NA	NA	CHEMBL328710	6450842	NA
Reserpine	NA	Caenorhabditis elegans	N2	30 µM	31	NA	NA	NA	18409080	NA	RESERPINE	CHEMBL772	5770	DB00206
Succinate	NA	Caenorhabditis elegans	N2	10 mM	4	NA	NA	NS	25643626	NA	NA	CHEMBL576	NA	DB00139
N-acetylglucosamine	GlcNAc or NAG	Caenorhabditis elegans	N2	10 mM	50	NA	NA	NA	24630720	NA	NA	CHEMBL447878	NA	DB00141
Glutamate	NA	Caenorhabditis elegans	N2	1 mM	14	NA	NA	NA	25643626	NA	NA	CHEMBL575060	NA	DB00142
Nectarine	NA	Drosophila melanogaster	Canton S	0.04	17.6	2.7	Female	NA	21406223	Mix	NA	NA	NA	NA
Glutathione	NA	Caenorhabditis elegans	N2	25µL Liposomes + 360µg glutathione	NA	50	NA	NA	19580823	NA	GLUTATHIONE	CHEMBL1543	25246407, 124886	DB00143
Guanabenz acetate	NA	Caenorhabditis elegans	NA	88 µM	12	NA	NA	NA	24134630	NA	GUANABENZ ACETATE	CHEMBL1200560	9570374, 5702062	DB00629
Danazol	NA	Caenorhabditis elegans	NA	33 µM	13	NA	NA	NA	24134630	NA	DANAZOL	CHEMBL1479	28417	DB01406
Glycine	NA	Caenorhabditis elegans	N2	5 mM	3	NA	NA	NS	25643626	NA	GLYCINE	CHEMBL773	750, 5257127	DB00145
Creatine	NA	Mus musculus	C57BL/6J	0.01	8	3.5	Female	NA	17416441	NA	CREATINE	CHEMBL283800	59098743, 586	DB00148
Electrolyzed reduced water	TI-200 ERW	Caenorhabditis elegans	N2	NA	41	0	NA	NA	20944427	Mix	NA	NA	NA	NA
KN-93	NA	Drosophila melanogaster	Oregon R	10-100 µM	20	NA	NA	NA	22363408	NA	NA	CHEMBL155333	NA	NA
Tryptophan	NA	Caenorhabditis elegans	N2	1 mM	14	NA	NA	NA	25643626	NA	TRYPTOPHAN	CHEMBL54976	6305, 6923516	DB00150
Erchen wan	EC	Caenorhabditis elegans	N2	1.5 g/L	21.8	NA	NA	NA	24952637	Mix	NA	NA	NA	NA
Glucose	Dextrose; D-glucose	Saccharomyces cerevisiae	PSY316	10%	19.8	NA	NA	NA	12391171	NA	NA	CHEMBL1222250	NA	DB09341
Butein	NA	Saccharomyces cerevisiae	PSY316AT MAT_	10 µM	31	NA	NA	NA	12939617	NA	BUTEIN	CHEMBL128000	5281222	NA
Threonine	NA	Caenorhabditis elegans	N2	5 mM	3	NA	NA	NS	25643626	NA	THREONINE	CHEMBL291747	6288, 6971019	DB00156
Folic acid	NA	Caenorhabditis elegans	N2	50 µM	0.2	NA	NA	NS	26546011	NA	FOLIC ACID	CHEMBL1622	6037	DB00158
HF-HQ	NA	Caenorhabditis elegans	N2	400 µM	20	NA	NA	NA	22529848	Mix	NA	NA	NA	NA
Alanine	NA	Caenorhabditis elegans	N2	1 mM	8	NA	NA	NA	25643626	NA	ALANINE	CHEMBL12198	57383916, 602	DB00160
Platinum nanoparticles	nano-Pt	Caenorhabditis elegans	N2	0.5 mM	22	NA	NA	NA	18400258	Mix	NA	NA	NA	NA
Gallic Acid	NA	Caenorhabditis elegans	N2	300 µM	10	NA	NA	NA	21805983	NA	GALLIC ACID	CHEMBL288114	370	NA
Valine	NA	Caenorhabditis elegans	N2	1 mM	13	NA	NA	NS	25643626	NA	VALINE	CHEMBL43068	6287, 88733505, 6971018	DB00161
Isoleucine	NA	Caenorhabditis elegans	N2	1 mM	3	NA	NA	NS	25643626	NA	ISOLEUCINE	CHEMBL1233584	7043901, 6306	DB00167
N-tert-butyl-alpha-phenylnitrone	PBN; alpha phenyl-N-tert butyl nitrone	Mus musculus	C57BL/6J	0.25 mg/ml of water	3.8	5	Male	NA	9614711	NA	NA	CHEMBL13210	NA	NA
Alpha-lipoic acid	Lipoic acid	Drosophila melanogaster	Canton S	0.00005	12	5	Female	NA	15328413	NA	NA	CHEMBL33864	NA	DB00166
Protocatechuic acid	NA	Caenorhabditis elegans	N2	100  µM	23	25	NA	NA	23780797	NA	PROTOCATECHUIC ACID	CHEMBL37537	72	DB03946
Gluconic acid	NA	Drosophila melanogaster	Oregon R	1 M	-9.3	NA	Male	NA	110607	NA	GLUCONIC ACID	CHEMBL464345	10690	DB13180, DB09408
Vitamin D3	NA	Caenorhabditis elegans	N2	1000 µg/ml	23	NA	NA	NA	24304198	NA	NA	CHEMBL1042	NA	DB00169
Proline	L-proline	Caenorhabditis elegans	N2	5 uM	5.8	NA	NA	NA	22482728	NA	PROLINE	CHEMBL54922, CHEMBL72275	NA	DB00172
3,4-dihydroxybenzaldehyde	protocatechuic aldehyde	Drosophila melanogaster	yw (y1w67c23)	0.3 mM	13	NA	Female	NA	22809229	NA	NA	CHEMBL222021	NA	DB11268
Asparagine	NA	Caenorhabditis elegans	N2	1 mM	1	NA	NA	NS	25643626	NA	ASPARAGINE	CHEMBL58832	6267, 6992089	DB00174
Freeze dried royal jelly	FDRJ	Drosophila melanogaster	Oregon R	1% w/v	8.5	-4	Male	NA	23132575	Mix	NA	NA	NA	NA
Caffeine	NA	Drosophila melanogaster	Oregon R	0.01 mg/ml	-10.1	NA	Male	NS	8326745	NA	CAFFEINE	CHEMBL113	2519	DB00201
DL-lactate	NA	Caenorhabditis elegans	N2	5 mM	6	NA	NA	NA	25643626	NA	NA	CHEMBL1357	NA	NA
Rifamycin SV	NA	Caenorhabditis elegans	N2	50 µM	20.9	NA	NA	NA	25720500	NA	NA	CHEMBL437765	NA	DB11753, DB05378
Doxycycline	NA	Caenorhabditis elegans	N2	30 µg/ml	36.5	NA	NA	NA	23698443	NA	DOXYCYCLINE	CHEMBL1433, CHEMBL1200699	NA	DB00254
Metoprolol	NA	Mus musculus	C3B6F1	1.1 g/kg diet	10	NA	Male	NA	23314750	NA	METOPROLOL	CHEMBL13	4171	DB00264
Sodium borate	NA	Drosophila melanogaster	Oregon R	0.01 M	-69.2	NA	Male	NA	7889879	NA	SODIUM BORATE	CHEMBL3833375	16211214	DB14505, DBSALT002513
D-xylitol	NA	Saccharomyces cerevisiae	PSY316	1 M	36.8	NA	NA	NA	12391171	NA	NA	CHEMBL1865120	NA	DB01904
Acarbose	ACA	Mus musculus	UM-HET3	1000mg/kgdiet	5	9	Female	NA	24245565	NA	ACARBOSE	CHEMBL404271, CHEMBL1566	NA	DB00284
Morphine	NA	Drosophila melanogaster	Oregon R	NA	3.2	NA	NA	NA	21061062	NA	MORPHINE	CHEMBL70	5288826	DB00295, DB05354
Nicotinamide	Vitamin B3	Caenorhabditis elegans	N2	100 µM	6.5	6	NA	NA	24077178	NA	NA	CHEMBL1140	NA	DB02701
Valproic acid	NA	Caenorhabditis elegans	N2	6 mM	35	42	NA	NA	18248662	NA	VALPROIC ACID	CHEMBL109	3121	DB00313, DB00510
Doxazosin mesylate	NA	Caenorhabditis elegans	NA	33 µM	15	NA	NA	NA	24134630	NA	DOXAZOSIN MESYLATE	CHEMBL1200561	25137856, 45039113, 62978	DB00590
Acetaminophen	NA	Caenorhabditis elegans	N2	0.0001	48.6	59	NA	NA	22114686	NA	ACETAMINOPHEN	CHEMBL112	1983	DB00316
Korean mistletoe extract	Viscum album coloratum extract	Drosophila melanogaster	Canton S	50 µg/ml	19.9	NA	NA	NA	24337961	Mix	NA	NA	NA	NA
Chloramphenicol	NA	Caenorhabditis elegans	N2	100 µg/ml	15.8	NA	NA	NA	23698443	NA	CHLORAMPHENICOL	CHEMBL130	5959	DB00446
Metformin	NA	Rattus norvegicus	Fischer 344	300 mg/kg/day	2.3	2.1	NA	NS	20304770	NA	METFORMIN	CHEMBL1431	4091	DB00331
Cranberry anthocyanin extract	NA	Drosophila melanogaster	Oregon-R-C	5 mg/ml	6.3	0	"
"	NA	26159161	Mix	NA	NA	NA	NA
Trimethadione	NA	Caenorhabditis elegans	N2	4 mg/ml	47	57	NA	NA	15653505	NA	TRIMETHADIONE	CHEMBL695	5576	DB00347
Dimethyl sulfoxide	NA	Caenorhabditis elegans	N2	0.005	29	18.6	NA	NA	20828537	NA	NA	CHEMBL504	679	DB01093
Loxapine succinate	NA	Caenorhabditis elegans	NA	88µM	43	NA	NA	NA	24134630	NA	LOXAPINE SUCCINATE	CHEMBL1201155	71399, 25137852	DB00408
Butylated hydroxytoluene	NA	Mus musculus	BaLB/c	NA	15.8	NA	Female	NA	448040	NA	BUTYLATED HYDROXYTOLUENE	CHEMBL146	31404	NA
Ampicillin	NA	Caenorhabditis elegans	fem-1(hc17)	100µg/ml	34	NA	NA	NA	16441844	NA	NA	CHEMBL174	NA	DB00415
Lithium Chloride	NA	Caenorhabditis elegans	N2	10 mM	36	NA	NA	NA	17959600	NA	NA	CHEMBL69710	NA	NA
Thyroxin	T4	Rattus norvegicus	Wistar	0.5 µg/g bodyweight	-3.5	NA	Female	NA	6632988	NA	NA	CHEMBL1624	NA	DB00451
Cranberry Extract	CBE	Caenorhabditis elegans	N2	2 mg/mL	32.5	NA	NA	NA	22864793	Mix	NA	NA	NA	NA
Lamotrigine	NA	Drosophila melanogaster	Ives	12 mg/ml	15.4	NA	Male	NA	19430925	NA	LAMOTRIGINE	CHEMBL741	3878	DB00555
Loratadine	NA	Caenorhabditis elegans	NA	33 µM	18	NA	NA	NA	24134630	NA	LORATADINE	CHEMBL998	3957	DB00455
Celecoxib	NA	Caenorhabditis elegans	N2	10µm	19	NA	NA	NA	21348927	NA	CELECOXIB	CHEMBL118	2662	DB00482
Gluconate	NA	Caenorhabditis elegans	N2	5 mM	17	NA	NA	NA	25643626	NA	NA	CHEMBL464345	NA	DB13180
Nortriptyline hydrochloride	NA	Caenorhabditis elegans	NA	88 µM	21	NA	NA	NA	24134630	NA	NORTRIPTYLINE HYDROCHLORIDE	CHEMBL1201156	657214, 441358, 13468	"DBSALT000641
"
Vincristine sulfate	NA	Caenorhabditis elegans	NA	88µM	12	NA	NA	NA	24134630	NA	VINCRISTINE SULFATE	CHEMBL501867	249332	"DBSALT000314
"
Amoxapine	NA	Caenorhabditis elegans	NA	88 µM	33	NA	NA	NA	24134630	NA	AMOXAPINE	CHEMBL1113	2170	DB00543
HA-1077	NA	Drosophila melanogaster	Oregon R	10 µM	14.5	NA	NA	NA	22363408	NA	NA	CHEMBL541388	NA	DB08162, DB12469
Minocycline hydrochloride	NA	Caenorhabditis elegans	NA	88 µM	29	NA	NA	NA	24134630	NA	MINOCYCLINE HYDROCHLORIDE	CHEMBL1200881	NA	DBSALT000721
Cinnarizine	NA	Caenorhabditis elegans	NA	33 µM	15	NA	NA	NA	24134630	NA	CINNARIZINE	CHEMBL43064	1547484	DB00568
Eleutherococcus senticosus root extract	NA	Caenorhabditis elegans	N2	250 µg/ml	16	NA	NA	NA	18536978	Mix	NA	NA	NA	NA
L-Carnitine	Acetyl-L-carnitine	Saccharomyces cerevisiae	BY4741	1 mM	140	NA	NA	NS	20550520	NA	NA	CHEMBL1149	NA	DB00583
Ethosuximide	NA	Caenorhabditis elegans	N2	4 mg/ml	35	37	NA	NA	15653505	NA	ETHOSUXIMIDE	CHEMBL696	3291	DB00593
L-deprenyl	NA	Rattus norvegicus	Fischer 344	0.0025	16.7	17	NA	NA	2118586	NA	NA	CHEMBL972	NA	DB01037
Demeclocycline hydrochloride	NA	Caenorhabditis elegans	NA	33 µM	16	NA	NA	NA	24134630	NA	DEMECLOCYCLINE HYDROCHLORIDE	CHEMBL1200474	NA	DBSALT000040
Nicardipine hydrochloride	NA	Caenorhabditis elegans	NA	176 µM	23	NA	NA	NA	24134630	NA	NICARDIPINE HYDROCHLORIDE	CHEMBL1200326	49853450, 41114	DBSALT000499
Bacitracin	NA	Caenorhabditis elegans	N2	0.01	58.5	74	NA	NA	22114686	Peptide	NA	NA	NA	NA
Green tea extract	NA	Drosophila melanogaster	Oregon R	Instead of water	8.6	NA	Male	NA	8326745	Mix	NA	NA	NA	NA
Branched-Chain Amino Acids	BCAAs; Branched-Chain Amino Acids	Mus musculus	B6.129S2	1.5 mg/g body weight	12	0	NA	NA	20889128	Peptide	NA	NA	NA	NA
Simvastatin	NA	Drosophila melanogaster	NA	240 µM	25	NA	NA	NA	22737247	NA	SIMVASTATIN	CHEMBL1064	54454	DB00641
BRL 15572	NA	Caenorhabditis elegans	NA	33 µM	10	NA	NA	NA	24134630	NA	NA	CHEMBL534232	3654103	NA
Wortmannin	NA	Drosophila melanogaster	Canton S	5 µM	5	NA	Male	NA	24096697	NA	WORTMANNIN	CHEMBL428496	312145	DB08059
Sevelamer	NA	Drosophila melanogaster	yw	1%	16	NA	Male	NA	22942172	NA	SEVELAMER	CHEMBL1201798	3085017	DB00658
Thioridazine hydrochloride	NA	Caenorhabditis elegans	NA	33µM	31	NA	NA	NA	24134630	NA	THIORIDAZINE HYDROCHLORIDE	CHEMBL1200916	657213, 66062	DBSALT000503
Myxothiazol	NA	Caenorhabditis elegans	N2	NA	32	28.6	NA	NA	18221415	NA	MYXOTHIAZOL	CHEMBL454568	10972974	DB04741
Ethanol	NA	Caenorhabditis elegans	N2	4 mM	111.9	NA	NA	NA	22279556	NA	NA	CHEMBL545	NA	DB00898
AG-490	NA	Drosophila melanogaster	Oregon R	300 µM	17.5	NA	NA	NA	22363408	NA	NA	CHEMBL56543	NA	NA
Blueberry extract	NA	Drosophila melanogaster	NA	5 mg/ml	10	NA	NA	NA	22197903	Mix	NA	NA	NA	NA
Cortisone	NA	Asplanchna brightwelli	clone 4B61	400 µM	-3.2	0	NA	NS	2782995	NA	CORTISONE	CHEMBL111861	5867	DB14681
Phenformin	NA	Mus musculus	C3H/Sn	2 mg, 5 times a week	21	26	Female	NA	14618027	NA	PHENFORMIN	CHEMBL170988	8249	DB00914
Salicylic acid	NA	Caenorhabditis elegans	N2	1 µM	13.9	NA	NA	NA	22866967	NA	SALICYLIC ACID	CHEMBL424	118212070, 338	DB00936, DB01398
C60	Fullerene	Rattus norvegicus	NA	1.7 mg/kg of body weight	90	NA	NA	NA	22498298	NA	NA	NA	123591	NA
Aspirin	NA	Mus musculus	UM-HET3	2.5g /kg food	8	0	Male	NA	18631321	NA	ASPIRIN	CHEMBL25	2244	DB00945
3,5-dihydroxy-4Í-ethyl-trans-stilbene	3,5-hydroxy-4Í-ethyl-stilbene	Saccharomyces cerevisiae	PSY316AT_	10 µM	51.5	NA	NA	NA	17156081	NA	NA	NA	6439521	NA
Crude BB extract (Vaccinium angustifolium)	NA	Caenorhabditis elegans	fem-1(hc17)	1.5 mg/mL	37	NA	NA	NA	16441844	Mix	NA	NA	NA	NA
Sorbitol	D-sorbitol; Glucitol	Saccharomyces cerevisiae	PSY316	1 M	29.9	NA	NA	NA	12391171	NA	SORBITOL	CHEMBL1682	5780	DB01638, DB09391
Minocycline	NA	Drosophila melanogaster	Oregon	0.05 mM	49	NA	Male	NA	22330257	NA	MINOCYCLINE	CHEMBL1434	NA	DB01017
Guanfacine hydrochloride	NA	Caenorhabditis elegans	NA	13 µM	15	NA	NA	NA	24134630	NA	GUANFACINE HYDROCHLORIDE	CHEMBL1200494	71401, 60204077	DBSALT000509
Fenofibrate	NA	Caenorhabditis elegans	N2	10 µm	19	NA	NA	NA	23603800	NA	FENOFIBRATE	CHEMBL672	3339	DB01039, DB09545
BTCP hydrochloride	NA	Caenorhabditis elegans	NA	88 µM	14	NA	NA	NA	24134630	NA	NA	CHEMBL1255586	NA	NA
Turmeric powder	Curcuma longa	Drosophila melanogaster	NA	5 g/L	17.6	NA	NA	NA	24967413	Mix	NA	NA	NA	NA
Rifampicin	NA	Caenorhabditis elegans	N2	5 µM	42.6	NA	NA	NA	25720500	NA	NA	CHEMBL374478	NA	DB01045
Agmatine	NA	Caenorhabditis elegans	N2	100 µM	1	NA	NA	NS	25643626	NA	AGMATINE	CHEMBL58343	199	DB08838
Nitrendipine	NA	Caenorhabditis elegans	NA	88 µM	25	NA	NA	NA	24134630	NA	NITRENDIPINE	CHEMBL475534	4507	DB01054
Trolox	6-hydroxy-2,5,7, 8-tetramethylchroman-2-carboxylic acid	Caenorhabditis elegans	N2	3 mM	31	NA	NA	NA	18755260	NA	TROLOX	CHEMBL153	40634	NA
Promethazine hydrochloride	NA	Caenorhabditis elegans	NA	176 µM	32	NA	NA	NA	24134630	NA	PROMETHAZINE HYDROCHLORIDE	CHEMBL1200750	6014, 89044377, 657263, 517306	DBSALT000427
Chlorprothixene hydrochloride	NA	Caenorhabditis elegans	NA	13µM	33	NA	NA	NA	24134630	NA	CHLORPROTHIXENE HYDROCHLORIDE	CHEMBL1256658	5282478, 74765286	NA
Pergolide methanesulfonate	NA	Caenorhabditis elegans	NA	13 µM	37	NA	NA	NA	24134630	NA	NA	CHEMBL1275	NA	DB01186
Acetic Acid	NA	Caenorhabditis elegans	N2	50 ppm	23	NA	NA	NA	19837596	NA	ACETIC ACID	CHEMBL539	21980959, 176	DB03166, DB04184
Curare	NA	Asplanchna brightwelli	NA	0.00%	-24	NA	NA	NA	3833547	NA	NA	CHEMBL292280	NA	NA
Oxaloacetate	Oxaloacetic acid	Caenorhabditis elegans	N2	8 mM	25	13	NA	NA	19793063	NA	OXALOACETATE	CHEMBL1794791	970	NA
D-glucosamine	NA	Saccharomyces cerevisiae	W303R	0.5 mg/ml	0	NA	NA	NS	11805047	NA	NA	CHEMBL493287	NA	DB01296
Genistein	NA	Caenorhabditis elegans	N2	50 µM	10	NA	NA	NA	25593647	NA	GENISTEIN	CHEMBL44	5280961	DB01645
Tocotrienol	vitamin E; alpha-tocophero; alpha-tocotrienol; gamma-tocotrienol; and sigma-tocotrienol	Caenorhabditis elegans	N2	8 ug/ml	8.7	NA	NA	NA	10843344	NA	NA	CHEMBL120643	NA	DB12647
Everolimus	NA	Drosophila melanogaster	Oregon R	3 mM	16.6	NA	NA	NA	22363408	NA	EVEROLIMUS	CHEMBL1908360	6442177	DB01590
Apple peel	NA	Saccharomyces cerevisiae	MCY4/KlLSM4::kanMX4	1 gr	28.5	NA	NA	NS	22970337	Mix	NA	NA	NA	NA
Whole apple extract	NA	Caenorhabditis elegans	N2	10 mg/ml	39	25	NA	NA	23878618	Mix	NA	NA	NA	NA
Echinacea purpurea root	NA	Mus musculus	BALB/cByJ	2 mg/day	NA	28	Male	NA	16041619	Mix	ECHINACEA PURPUREA ROOT	NA	NA	NA
SP600125	NA	Drosophila melanogaster	Oregon R	10 mM	23.5	NA	NA	NA	22363408	NA	NA	CHEMBL7064	8515	DB01782
Ascr#3	hydroxy ketone ascaroside	Caenorhabditis elegans	N2	400 nM	21	NA	NA	NA	23509272	NA	NA	CHEMBL1221889	16066476	NA
Phosphoenolpyruvate	NA	Caenorhabditis elegans	N2	1 mM	12	NA	NA	NA	25643626	NA	PHOSPHOENOLPYRUVATE	CHEMBL1235228	1005, 59658623, 58114173	DB01819
EUK-8	NA	Caenorhabditis elegans	N2	10 mM	29	NA	NA	NA	10968795	NA	NA	NA	171249	NA
Matairesinol	NA	Caenorhabditis elegans	N2	10 uM	14	NA	NA	NA	26141518	NA	MATAIRESINOL	CHEMBL425148	119205	DB04200
Specioside	NA	Caenorhabditis elegans	N2	50 uM	11.8	NA	NA	NA	25619942	NA	SPECIOSIDE	CHEMBL2332355	11948661	NA
Damnacanthus officinarum root extract	NA	Caenorhabditis elegans	N2	1200 µg/mL	30.3	NA	NA	NA	22370553	Mix	NA	NA	NA	NA
Taurine	NA	Caenorhabditis elegans	N2	1 mM	11	NA	NA	NA	25643626	NA	TAURINE	CHEMBL239243	1123, 4068592	DB01956, DB11103
Rasayana	NA	Drosophila melanogaster	Oregon-K	1 drop	51.1	NA	Female	NA	21836798	Mix	NA	NA	NA	NA
Apple polyphenols	NA	Caenorhabditis elegans	N2	100 µg/ml	12	NA	NA	NA	20717869	Mix	NA	NA	NA	NA
Staurosporine	NA	Drosophila melanogaster	Oregon R	30-50 µM	34.8	NA	NA	NA	22363408	NA	STAUROSPORINE	CHEMBL388978	44259	DB02010
Quercetin dihydrate	NA	Drosophila melanogaster	Oregon R	1 mM	23	NA	NA	NA	22363408	NA	QUERCETIN DIHYDRATE	CHEMBL1173475	16212154	NA
N-(3-(aminomethyl)benzyl)acetamidine	NA	Drosophila melanogaster	Canton S	0.03 µ_	3	13	Male	NA	24096697	NA	NA	CHEMBL107251	NA	DB02044
Dichloroacetate	NA	Caenorhabditis elegans	N2	50 µg/ml	7.9	13.5	NA	NA	21153705	NA	NA	NA	25975	DB08809
N-butanol	NA	Caenorhabditis elegans	N2	4 mM	108.1	NA	NA	NA	22279556	NA	NA	CHEMBL14245	NA	DB02145
Taxifolin	NA	Caenorhabditis elegans	N2	820 µM	51	NA	NA	NA	18755260	NA	TAXIFOLIN	CHEMBL337309	471	DB02224
7-cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine	NA	Caenorhabditis elegans	NA	33 µM	11	NA	NA	NA	24134630	NA	NA	CHEMBL47940	6603792	NA
Myricetin	NA	Caenorhabditis elegans	N2	100 µM	32.9	NA	NA	NA	23736695	NA	MYRICETIN	CHEMBL164	5281672	DB02375
DhHP-6	Deuterohemin-AlaHisThrValGluLys	Caenorhabditis elegans	N2	200 µM	21	NA	NA	NA	20528576	Peptide	NA	NA	NA	NA
Geldanamycin	NA	Caenorhabditis elegans	N2	20 µM	2	NA	NA	NA	26676933	NA	GELDANAMYCIN	CHEMBL278315	5288382	DB02424
Recombinant buckwheat trypsin inhibitor	NA	Caenorhabditis elegans	N2	5 uM	15.6	NA	NA	NA	25959406	Peptide	NA	NA	NA	NA
Pyrrolidine dithiocarbamate	NA	Drosophila melanogaster	NA	20 mg/l	16	NA	Female	NA	21483034	NA	PYRROLIDINE DITHIOCARBAMATE	CHEMBL399491	65351	NA
D-aspartate	NA	Caenorhabditis elegans	N2	1 mM	7	NA	NA	NS	25643626	NA	D-ASPARTATE	CHEMBL29757	83887	DB02655
LY-367,265	NA	Caenorhabditis elegans	NA	33µM	34	NA	NA	NA	24134630	NA	NA	CHEMBL1079460	NA	NA
Putrescine	NA	Caenorhabditis elegans	N2	1 mM	10	NA	NA	NA	25643626	NA	PUTRESCINE	CHEMBL46257	1045	DB01917
LY-294002	NA	Drosophila melanogaster	Canton S	5 µM	14	22.5	Male	NA	20017609	NA	LY-294002	CHEMBL98350	3973	DB02656
Huanshao dan	HSh	Caenorhabditis elegans	N2	6.8 g/L	38.3	NA	NA	NA	24952637	Mix	NA	NA	NA	NA
Clofibrate	NA	Caenorhabditis elegans	N2	10 µm	16	NA	NA	NA	23603800	NA	CLOFIBRATE	CHEMBL565	2796	DB00636
Resveratrol	NA	Saccharomyces cerevisiae	PSY316AT MAT_	10 µM	60.7	NA	NA	NA	12939617	NA	RESVERATROL	CHEMBL165	445154	DB02709
Pregnenolone	PREG	Caenorhabditis elegans	N2	60 µg/mL	20	NA	NA	NA	17266678	NA	PREGNENOLONE	CHEMBL253363	8955	DB02789
Bezafibrate	NA	Caenorhabditis elegans	N2	10 µm	13	NA	NA	NA	23603800	NA	BEZAFIBRATE	CHEMBL264374	39042	DB01393
Methylergonovine maleate	NA	Caenorhabditis elegans	NA	88µM	28	NA	NA	NA	24134630	NA	METHYLERGONOVINE MALEATE	CHEMBL1200843	5281072	DBSALT001025
Alpha-ketoglutarate	NA	Caenorhabditis elegans	N2	8 mM	29.4	NA	NA	NA	24828042	NA	NA	CHEMBL1686	NA	DB02926, DB03806
Beta-alanine	NA	Caenorhabditis elegans	N2	1 mM	13	NA	NA	NA	25643626	NA	BETA-ALANINE	CHEMBL297569	4755801, 239	DB03107
L-histidine methyl ester	NA	Caenorhabditis elegans	N2	100 µM	8	NA	NA	NA	25643626	NA	NA	CHEMBL54664	NA	NA
Ivabradine	NA	Mus musculus	C57BL/6J	50 mg/kg/day	6.2	NA	Male	NA	25589054	NA	IVABRADINE	CHEMBL471737	132999	DB09083
Cysteine	NA	Caenorhabditis elegans	N2	1 mM	9	NA	NA	NA	25643626	NA	CYSTEINE	CHEMBL863, CHEMBL54943	NA	DB00151, DB04443, DB09485
Spermidine	NA	Drosophila melanogaster	w1118	1 mM	30	NA	NA	NA	19801973	NA	SPERMIDINE	CHEMBL19612	1102	DB03566
N-propanol	NA	Caenorhabditis elegans	N2	4 mM	95.5	NA	NA	NA	22279556	NA	NA	CHEMBL14687	NA	DB03175
Pomegranate juice	NA	Drosophila melanogaster	Canton S	0.1	8	NA	Female	NA	25566518	Mix	NA	NA	NA	NA
Rotenone	NA	Caenorhabditis elegans	N2	100 nM	10	NA	Hermaphrodite	NA	24199155	NA	ROTENONE	CHEMBL429023	6758	DB11457
Quercetin	NA	Caenorhabditis elegans	N2	100 µM	19	15	NA	NA	18024103	NA	QUERCETIN	CHEMBL50	5280343	DB04216
D-glycerol	NA	Saccharomyces cerevisiae	PSY316	1 M	49.8	NA	NA	NA	12391171	NA	NA	CHEMBL692	NA	DB09462
Fumarate	NA	Caenorhabditis elegans	N2	10 mM	16	NA	NA	NA	23472183	NA	NA	NA	5460307	NA
Beta-Estradiol	NA	Caenorhabditis elegans	NA	33 µM	7	NA	NA	NA	24134630	NA	NA	CHEMBL135	NA	DB00783
Citrate	Sodium citrate; Citric acid	Mytilina brevispina	NA	0.25% on alternate days	51.7	NA	NA	NA	804507	NA	Citric acid	CHEMBL1261	311	DB04272
Beta-caryophyllene	NA	Caenorhabditis elegans	N2	25 uM	11.2	NA	NA	NA	24835194	NA	BETA-CARYOPHYLLENE	CHEMBL445740	5281515	NA
Trichostatin A	NA	Drosophila melanogaster	Canton S	10 µM	23.3	37	Male	NA	15346199	NA	NA	CHEMBL99	NA	DB04297
Panax notoginseng main root polysaccharide	NA	Caenorhabditis elegans	N2	0.1 mg/ml	21	NA	NA	NA	26234580	Mix	NA	NA	NA	NA
Allantoin	NA	Caenorhabditis elegans	N2	250 µM	21.9	NA	NA	NA	26676933	NA	ALLANTOIN	CHEMBL593429	204	DB11100
Lactic acid	NA	Drosophila melanogaster	Oregon R	1M	-32.7	NA	Male	NA	110607	NA	LACTIC ACID	CHEMBL1200559	612, 19789253	DB04398, DB09294
Homocysteine	NA	Caenorhabditis elegans	N2	5 mM	7	NA	NA	NA	25643626	NA	HOMOCYSTEINE	CHEMBL310604	778, 49791978	DB04422
Shengmai yin	SM	Caenorhabditis elegans	N2	48.0 g/L	47.3	NA	NA	NA	24952637	Mix	NA	NA	NA	NA
N-nitrosodimethylamine	NA	Caenorhabditis elegans	N2	50 µM	5.5	NA	NA	NA	25556763	NA	N-NITROSODIMETHYLAMINE	CHEMBL117311	6124	NA
Omega-6	_-6  Polyunsaturated fatty acids; Omega-6 PUFAs; Omega-6 Fatty Acid	Caenorhabditis elegans	N2	10 µM	16	NA	NA	NA	23392608	NA	NA	NA	56842208	NA
2,4-dinitrophenol	DNP	Drosophila melanogaster	Oregon R	0.008	20.2	0	NA	NA	16266268	NA	2,4-DINITROPHENOL	CHEMBL273386	1493	DB04528
Paraquat	N,N_-dimethyl-4,4_-bipyridinium dichloride	Caenorhabditis elegans	N2	0.1 mM	58	48	NA	NA	21151885	NA	PARAQUAT	CHEMBL74469	15939	NA
Hesperidin	NA	Saccharomyces cerevisiae	BY4741	5 µM	15.4	NA	NA	NA	22484922	NA	HESPERIDIN	CHEMBL449317	10621	DB04703
Carnosine	NA	Drosophila melanogaster	D-32	200 mg/l	24.3	NA	Male	NA	12447464	NA	NA	CHEMBL242948	NA	DB11695
Chicoric acid	NA	Caenorhabditis elegans	N2	100 µM	21	8	NA	NA	24244361	NA	CHICORIC ACID	CHEMBL29660	5470299	NA
Buformin	NA	Rattus norvegicus	LIO	5 mg/day	7	5.5	Female	NA	14618027	NA	BUFORMIN	CHEMBL39736	2468	DB04830
Vitamin E	D,1-alpha-tocopherol	Caenorhabditis elegans	N2	400 µg/ml	4	NA	NA	NA	3374177	NA	VITAMIN E	CHEMBL47, CHEMBL3989727	NA	DB00163
EGTA	1,2-di(2 aminoethoxy)ethane tetra-acetic acid	Mytilina brevispina	NA	0.25% on alternate days	75.9	NA	NA	NA	804507	NA	NA	CHEMBL240390	NA	NA
Nebivolol	NA	Mus musculus	C3B6F1	0.27 g/kg diet	6.4	NA	Male	NA	23314750	NA	NEBIVOLOL	CHEMBL434394	71301	DB04861
Liuwei dihuang wan	LW	Caenorhabditis elegans	N2	4.2 g/L	12.6	NA	NA	NA	24952637	Mix	NA	NA	NA	NA
Huperzine A	NA	Caenorhabditis elegans	N2	300 µM	13.8	NA	NA	NA	23523941	NA	HUPERZINE A	CHEMBL1255901	9794806	DB04864, DB01928, DB05510
Mianserin	NA	Caenorhabditis elegans	N2	50 µM	31	NA	NA	NA	18033297	NA	MIANSERIN	CHEMBL6437	4184	DB06148
Ginkgo biloba extract	EGb 761	Rattus norvegicus	Fischer 344	50 mg/kg	17.4	NA	Male	NA	9469738	Mix	NA	NA	NA	NA
DAPH	NA	Caenorhabditis elegans	NA	13 µM	15	NA	NA	NA	24134630	NA	DAPH	CHEMBL268868	1697	NA
N-acetyl-L-cysteine	NA	Drosophila melanogaster	Oregon R	1 mg/ml	14.1	15.1	Male	NA	9447249	NA	NA	CHEMBL600	NA	DB06151, DB05436
Polyphenols	NA	Mus musculus	C57BL/6J	NA	6.3	NA	Male	NA	22265987	Mix	NA	NA	NA	NA
Lonidamine	NA	Caenorhabditis elegans	NA	5 µM	8	8	NA	NA	21932172	NA	LONIDAMINE	CHEMBL1257030	39562	DB06266, DB03762
Cyproterone acetate	NA	Caenorhabditis elegans	NA	33 µM	23	NA	NA	NA	24134630	NA	CYPROTERONE ACETATE	CHEMBL139835	9880	DB04839
Astaxanthin	NA	Caenorhabditis elegans	N2	1 mM	28.6	21.7	NA	NA	22013497	NA	ASTAXANTHIN	CHEMBL1255871	5281224	DB06543
Betaine	Trimethylglycine	Caenorhabditis elegans	N2	1 mM	9	NA	NA	NA	25643626	NA	BETAINE	CHEMBL95889	248	DB06756
4-phenylbutyrate	PBA	Drosophila melanogaster	Canton S	5 mM	40	41	NA	NA	11792861	NA	NA	CHEMBL1469	NA	DB06819, DB02000, DB12600
Fisetin	NA	Saccharomyces cerevisiae	PSY316AT MAT_	10 µM	55	NA	NA	NA	12939617	NA	FISETIN	CHEMBL31574	5281614	DB07795
Tyrphostin 9	NA	Drosophila melanogaster	Oregon R	300-500 µM	17.3	NA	NA	NA	22363408	NA	NA	CHEMBL7917	NA	NA
Sodium hypophosphite	NA	Zaprionus paravittiger	NA	1 mM	-89.8	-94.9	Female	NA	3721207	NA	SODIUM HYPOPHOSPHITE	CHEMBL2146115	23675242	NA
D-beta-hydroxybutyrate	D-_HB	Caenorhabditis elegans	N2	20 mM	26	NA	NA	NA	25127866	NA	NA	CHEMBL1162484	NA	NA
Naphthazarin	NA	Caenorhabditis elegans	N2	100 µM	11	12	NA	NA	21765926	NA	NA	CHEMBL274056	NA	NA
Trametinib	NA	Drosophila melanogaster	white Dahomey	15.6 µM	12	NA	NA	NA	26119340	NA	TRAMETINIB	CHEMBL2103875	11707110	DB08911
Acacetin 7-O-alpha-l-rhamnopyranosyl (1_2) beta-D-xylopyranoside	NA	Caenorhabditis elegans	N2	50 µM	17	NA	NA	NA	26433219	NA	NA	NA	5317025	NA
Melatonin	NA	Mus musculus	BALB/c	NA	18.1	NA	Female	NA	8290600	NA	MELATONIN	CHEMBL45	896	DB01065, DB08189
Methylene blue	MB	Mus musculus	UM-HET3	27mg/kg diet	0	6	Female	NA	24245565	NA	METHYLENE BLUE	CHEMBL191083, CHEMBL550495	NA	DB09241
Coenzyme Q10	Q10	Caenorhabditis elegans	N2	50 µg/ml	6	NA	NA	NA	14706236	NA	NA	CHEMBL454801	NA	DB09270
Tannic acid	NA	Drosophila melanogaster	Oregon R	1 mg/ml	0	NA	Male	NS	8326745	NA	TANNIC ACID	CHEMBL506247	16129778	DB09372
Xylose	NA	Caenorhabditis elegans	N2	10 mM	6	NA	NA	NA	25643626	NA	XYLOSE	CHEMBL502135	135191	DB09419
Tartaric acid	NA	Drosophila melanogaster	Oregon R	0.1M	-72	NA	Male	NA	110607	NA	TARTARIC ACID	CHEMBL1200861	439655	DB09459
Glaucarubinone	NA	Caenorhabditis elegans	N2	100 nM	7.9	9	NA	NA	21264793	NA	GLAUCARUBINONE	CHEMBL458347	441796	NA
Glycerol	NA	Caenorhabditis elegans	N2	1%	-36	NA	NA	NA	19883616	NA	NA	CHEMBL692	NA	DB09462, DB04077
Olive Oil	NA	Rattus norvegicus	NA	NA	18	NA	NA	NA	22498298	Mix	OLIVE OIL	NA	NA	NA
Apple	NA	Saccharomyces cerevisiae	MCY4/KlLSM4::kanMX4	1 gr	78.5	NA	NA	NS	22970337	Mix	NA	NA	NA	NA
Sesame	NA	Drosophila melanogaster	Oregon R	2 mg/ml	12	NA	Male	NA	23291977	Mix	NA	NA	NA	NA
Cocoa	Cocoa powder	Drosophila melanogaster	rosy^+5	50 g/l medium	NA	NA	Male	NA	19083435	Mix	COCOA	NA	NA	NA
Proanthocycanidin	NA	Caenorhabditis elegans	N2	67 µg/ml	36.6	NA	NA	NA	22509764	Mix	NA	NA	NA	NA
Calcium gluconate	NA	Drosophila melanogaster	Oregon R	0.001 M	-3.7	NA	Male	NA	110607	NA	CALCIUM GLUCONATE	CHEMBL2106119	9290, 10982878	DB11126
L-Theanine	NA	Caenorhabditis elegans	N2	0.1 µM	3.6	4.4	NA	NA	22422488	NA	NA	CHEMBL3039113	NA	DB12444
Polydatin	NA	Caenorhabditis elegans	N2	1 mM	30	NA	NA	NA	24305800	NA	NA	CHEMBL142652	NA	DB11263
Platycladus orientalis seed extract	NA	Caenorhabditis elegans	N2	500 µg/ml	26.5	NA	NA	NA	23523941	Mix	NA	NA	NA	NA
Dimethyl formamide	DMF	Caenorhabditis elegans	N2	0.0075	33	54	NA	NA	23313473	NA	NA	CHEMBL268291	NA	DB01844
Curcumin	NA	Drosophila melanogaster	Canton S	100 µM	19	NA	Female	NA	20645870	NA	CURCUMIN	CHEMBL116438	5281767	DB11672
Galactose	D-galactose	Musca domestica	NA	20 mg/ml	-27.1	-27.1	Male	NA	15547319	NA	GALACTOSE	CHEMBL1233058	439357	DB11735
Epicatechin	NA	Drosophila melanogaster	Oregon R	0.01 mg/ml	1.8	NA	Male	NS	8326745	NA	NA	CHEMBL583912	NA	DB12039
Icariin	NA	Caenorhabditis elegans	N2	45 µM	20.7	NA	NA	NA	22216122	NA	ICARIIN	CHEMBL553204	5318997	NA
Otophylloside B	NA	Caenorhabditis elegans	N2	50 µM	30	NA	NA	NA	26112394	NA	NA	NA	10079485	NA
Vinpocetine	NA	Caenorhabditis elegans	NA	33µM	15	NA	NA	NA	24134630	NA	VINPOCETINE	CHEMBL71752	443955	DB12131
3,5-dihydroxy-4Í-acetoxy-trans-stilbene	3,5-hydroxy-4Í-acetoxy-stilbene	Saccharomyces cerevisiae	PSY316AT_	10 µM	68.2	NA	NA	NA	17156081	ID's Not Found	NA	NA	NA	NA
Trehalose	NA	Caenorhabditis elegans	N2	5 mM	32	NA	NA	NA	20477758	"
"	TREHALOSE	CHEMBL1236395	7427	DB12310
Polypeptide Bovine Thymus extract	NA	Mus musculus	C3H/Sn	0.5 mg	28	11.2	Female	NA	6752596	Mix	NA	NA	NA	NA
Indirubin	NA	Drosophila melanogaster	Oregon R	3 mM	8.2	NA	NA	NA	22363408	NA	INDIRUBIN	CHEMBL1276127	5318433	DB12379
L-theanine	Theanine	Caenorhabditis elegans	N2	100 µM	14	NA	NA	NA	25643626	NA	NA	CHEMBL3039113	NA	DB12444
Propyl gallate	NA	Zaprionus paravittiger	NA	25 µg/ml	8.7	15.3	Female	NA	8950031	NA	PROPYL GALLATE	CHEMBL7983	4947	DB12450
Sodium pyruvate	Pyruvic acid	Caenorhabditis elegans	N2	2.5 mM	13.9	NA	NA	NA	21040400	NA	NA	CHEMBL181886	NA	DBSALT001546
Eliprodil	NA	Caenorhabditis elegans	NA	88 µM	16	NA	NA	NA	24134630	NA	ELIPRODIL	CHEMBL28564	60703	DB12869
D-alanine	NA	Caenorhabditis elegans	N2	10 mM	16	NA	NA	NA	25643626	NA	D-ALANINE	CHEMBL66693	71080, 7311725	DB01786
Oxatomide	NA	Caenorhabditis elegans	NA	88 µM	25	NA	NA	NA	24134630	NA	OXATOMIDE	CHEMBL13828	4615, 1385580	DB12877
1-methyl nicotinamide	NA	Caenorhabditis elegans	N2	1 µM	7.7	11	NA	NA	24077178	NA	NA	CHEMBL71733	NA	DB11710
Quinidine sulfate	NA	Caenorhabditis elegans	NA	33 µM	12	NA	NA	NA	24134630	NA	QUINIDINE SULFATE	CHEMBL3707183	656862	DBSALT000363
Pinitol	NA	Drosophila melanogaster	Canton S	NA	12.5	NA	Female	NA	22843669	NA	PINITOL	CHEMBL493737	NA	DB12969
Ferulsinaic acid	NA	Caenorhabditis elegans	N2	100 µm	20	NA	NA	NA	21749391	NA	NA	NA	102469382	NA
Inositol	NA	Caenorhabditis elegans	N2	1 mM	3	NA	NA	NA	25643626	NA	INOSITOL	CHEMBL1222251	892	DB13178, DB11196
Plumbagin	NA	Caenorhabditis elegans	N2	1 µM	1	3	NA	NS	21765926	NA	PLUMBAGIN	CHEMBL295316	10205	NA
Nordihydroguaiaretic acid	NDGA	Aedes aegypti	NA	0.001% (w/v)	42.7	NA	Female	NA	3749035	NA	NORDIHYDROGUAIARETIC ACID	CHEMBL52	4534	DB00179, DB05900
Calcium lactate	NA	Drosophila melanogaster	Oregon R	0.01 M	-10.7	NA	Male	NA	110607	NA	CALCIUM LACTATE	CHEMBL2106111	521805, 13144	DB13231
Metergoline	NA	Caenorhabditis elegans	NA	33µM	23	NA	NA	NA	24134630	NA	METERGOLINE	CHEMBL19215	28693	DB13520
3,4-dichloroisocoumarin	NA	Caenorhabditis elegans	NA	88 µM	13	NA	NA	NA	24134630	NA	NA	CHEMBL24983	NA	DB04459
Fish oil	NA	Caenorhabditis elegans	N2	2 mg/plate	-12.8	NA	NA	NA	23526170	Mix	FISH OIL	NA	NA	NA
Catechin	NA	Drosophila melanogaster	Oregon R	0.1 mg/ml	-8.5	NA	Male	NS	8326745	NA	CATECHIN	CHEMBL206452	1203	DB14086
Nicotinamide adenine dinucleotide	NAD	Caenorhabditis elegans	N2	100 µM	15	NA	NA	NA	19370397	NA	NA	CHEMBL1234613	NA	DB14128
Royal Jelly	NA	Mus musculus	C3H/HeJ	500 ppm ad libitum in diet	23.6	NA	Male	NA	12954483	Mix	NA	NA	NA	NA
Edetate Calcium Disodium	ethylene diamine tetra-acetic acid (di-sodium salt); EDTA	Mytilina brevispina	NA	0.25% on alternate days	49.4	NA	NA	NA	804507	NA	EDETATE CALCIUM DISODIUM	CHEMBL1200375, CHEMBL3989522	NA	DB14598, DBSALT000837
Picolinic acid	NA	Caenorhabditis elegans	N2	1 mM	7	NA	NA	NA	25643626	NA	NA	CHEMBL72628	NA	NA
Tyrphostin 1	NA	Drosophila melanogaster	Oregon R	100-300 µM	19	NA	NA	NA	22363408	NA	TYRPHOSTIN 1	CHEMBL77456	2063	NA
Aurintricarboxylic acid	ATA	Drosophila melanogaster	Oregon R	0.5 mM	15	0	Male	NA	15621204	NA	AURINTRICARBOXYLIC ACID	CHEMBL275938	2259	NA
Juglone	5-hydroxy-1,4-naphthalenedione	Caenorhabditis elegans	N2	40µm	29	NA	NA	NA	19597959	NA	JUGLONE	CHEMBL43612	3806	NA
Kenpaullone	NA	Caenorhabditis elegans	NA	88 µM	27	NA	NA	NA	24134630	NA	KENPAULLONE	CHEMBL296586	3820	NA
Diiodomethane	Methylene iodide	Drosophila melanogaster	NA	10 µg/ml	29.3	NA	NA	NA	412727	NA	Diiodomethane	NA	6346	NA
Lithocholic acid	NA	Saccharomyces cerevisiae	BY4741	50 µM	100	NA	NA	NA	20622262	NA	LITHOCHOLIC ACID	CHEMBL1478	9903	NA
Tyrosol	NA	Caenorhabditis elegans	fer-15(b26)	250 µM	19.1	10.8	NA	NA	22824366	NA	TYROSOL	CHEMBL53566	10393	NA
Dibromoacetic acid	NA	Caenorhabditis elegans	N2	100 µm	14.6	NA	NA	NA	25556763	NA	DIBROMOACETIC ACID	CHEMBL449362	12433	NA
D-glutamate	NA	Caenorhabditis elegans	N2	10 mM	-3	NA	NA	NS	25643626	NA	D-GLUTAMATE	CHEMBL76232	23327	DB02517
Arctigenin	NA	Caenorhabditis elegans	N2	10 uM	6.7	NA	NA	NA	26141518	NA	ARCTIGENIN	CHEMBL435734	64981	NA
Sesamin	NA	Caenorhabditis elegans	N2	3.1 µg	10.5	NA	NA	NA	24549958	NA	SESAMIN	CHEMBL252915	72307	NA
Arctiin	NA	Caenorhabditis elegans	N2	10 uM	8.9	NA	NA	NA	26141518	NA	ARCTIIN	CHEMBL388452	100528	NA
Celastrol	NA	Caenorhabditis elegans	N2	7 µmol/l	17.4	NA	NA	NA	24416295	NA	CELASTROL	CHEMBL301982	122724	NA
Tetrahydrocurcumin	NA	Mus musculus	Sprague-Dawley	0.002	11.7	NA	Male	NA	15247057	NA	TETRAHYDROCURCUMIN	CHEMBL318743	124072	NA
Ketanserin tartrate	NA	Caenorhabditis elegans	NA	176 µM	13	NA	NA	NA	24134630	NA	KETANSERIN TARTRATE	CHEMBL1256709	135348	NA
Glyceollin I	NA	Saccharomyces cerevisiae	NA	12.5 nM	40	NA	NA	NA	24399048	NA	GLYCEOLLIN I	CHEMBL1774987	162807	NA
Nicotinamide riboside	NR	Saccharomyces cerevisiae	BY4741	10 µM	20	NA	NA	NS	17482543	NA	NICOTINAMIDE RIBOSIDE	CHEMBL438497	439924	NA
Tartrate	Sodium tartrate	Mytilina brevispina	NA	0.25% on alternate days	43.7	NA	NA	NA	804507	NA	TARTRATE	CHEMBL1236315	444305	NA
Sodium butyrate	NA	Drosophila melanogaster	Ra	10 mM	-9.1	NA	NA	NS	23044027	NA	SODIUM BUTYRATE	CHEMBL62381	5222465	NA
Baicalein	5,6,7-trihydroxyflavone	Caenorhabditis elegans	N2	0.001	36.7	52	NA	NA	22114686	NA	BAICALEIN	CHEMBL8260	5281605	NA
Tamarixetin	NA	Caenorhabditis elegans	NA	NA	28	NA	NA	NA	16872777	NA	TAMARIXETIN	CHEMBL226034	5281699	NA
Rosmarinic acid	NA	Caenorhabditis elegans	N2	200 µM	10	NA	NA	NA	21503726	NA	ROSMARINIC ACID	CHEMBL324842	5281792	NA
Piericidin A	NA	Caenorhabditis elegans	N2	100 nM	5	NA	NA	NA	24199155	NA	PIERICIDIN A	CHEMBL272733	6437838	NA
Myriocin	NA	Saccharomyces cerevisiae	BY4741	600 ng/ml	NA	NA	NA	NA	23725375	NA	MYRIOCIN	CHEMBL55076	6438394	NA
Naftopidil dihydrochloride	NA	Caenorhabditis elegans	NA	33 µM	14	NA	NA	NA	24134630	NA	NAFTOPIDIL DIHYDROCHLORIDE	CHEMBL1257069	6603044	NA
Verminoside	NA	Caenorhabditis elegans	N2	50 uM	8.5	NA	NA	NA	26189547	NA	VERMINOSIDE	CHEMBL462888	11948660	NA
Fucoxanthin	NA	Caenorhabditis elegans	N2	5 µM	14	24	NA	NA	26292053	NA	FUCOXANTHIN	CHEMBL1773903	54585187	NA
Thioflavin T	(4-(3,6-dimethyl-1,3-benzothiazol-3-ium-2- yl)-N,N-dimethylaniline chloride)	Caenorhabditis elegans	N2	50-100µM	60	78	NA	NA	21451522	NA	THIOFLAVIN T	CHEMBL224392	16953, 622721	NA
Propionylpromazine hydrochloride	NA	Caenorhabditis elegans	NA	33 µM	20	NA	NA	NA	24134630	NA	PROPIONYLPROMAZINE HYDROCHLORIDE	CHEMBL1256661	50986740, 24351	NA
Amperozide hydrochloride	NA	Caenorhabditis elegans	NA	13 µM	38	NA	NA	NA	24134630	NA	AMPEROZIDE HYDROCHLORIDE	CHEMBL1257106	73334, 50986842	NA
Polypeptide Pineal extract	PPE	Rattus norvegicus	NA	0.5 mg, 5 times a week	25	NA	Female	NA	575333	Mix	Organ extract, not a compound	NA	NA	NA
Thiazolidine carboxylic acid	TCA	Drosophila melanogaster	Oregon R	0.3% wt/vol	31	NA	NA	NA	6821144	NA	NA	CHEMBL3245365	NA	NA
Black tea extract	NA	Drosophila melanogaster	Oregon R	Instead of water	20.2	NA	Male	NA	8326745	Mix	NA	NA	NA	NA
Tea (Camellia sinensis) extract	NA	Drosophila melanogaster	Oregon R	Instead of water	15.7	NA	Male	NA	8326745	Mix	NA	NA	NA	NA
Butylated hydroxyanisole	BHA	Zaprionus paravittiger	NA	100 mM	-63.8	-53.7	Male	NA	9207858	NA	BUTYLATED HYDROXYANISOLE	CHEMBL192451, CHEMBL502074	8456	NA
Epithalamin	Pineal peptide Preparation	Mus musculus	C3H/Sn	NA	31	NA	NA	NA	9701766	NA	NA	NA	219042	NA
Rhodiola rosea extract	NA	Drosophila melanogaster	NA	30 mg/mL every other day	NA	42.9	Male	NA	9825229	Mix	NA	NA	NA	NA
EUK-134	NA	Caenorhabditis elegans	N2	0.05 mM	29	NA	NA	NA	10968795	NA	NA	NA	9823233	NA
Epitalon	Ala-Glu-Asp-Gly	Drosophila melanogaster	Canton S	5*10^-6 %	3.2	NA	Female	NS	11087911	NA	NA	NA	219042	NA
L-Glu-L-Trp dipeptide	NA	Rattus norvegicus	NA	5 µg/rat. 5 times a week	0	10.4	Female	NA	11707921	Peptide	NA	NA	NA	NA
Green tea polyphenols	NA	Mus musculus	Sprague-Dawley	80 mg/L	6.4	NA	Male	NA	15247057	Mix	NA	NA	NA	NA
3,3'-thiodipropionic acid	TDPA	Asplanchna brightwelli	clone 4B61	2 mM	10	0	NA	NA	15374519	NA	NA	CHEMBL1569439	NA	NA
3,3-diethyl-2-pyrrolidinone	DEABL	Caenorhabditis elegans	N2	2 mg/ml	31	49	NA	NA	15653505	NA	NA	CHEMBL293075	NA	NA
Dauer-inducing Pheromone	NA	Caenorhabditis elegans	N2	5% in food	13.3	NA	NA	NA	16377915	NA	NA	NA	11471380	NA
3,5-dihydroxy-4Í-thiomethyl-trans-stilbene	3,5-hydroxy-4Í-thiomethyl-stilbene	Saccharomyces cerevisiae	PSY316AT_	10 µM	22.7	NA	NA	NA	17156081	ID's Not Found	NA	NA	NA	NA
Epigallocatechin-3-gallate	EGCG	Caenorhabditis elegans	N2	25 µM	4.8	4.8	NA	NS	17156833	NA	NA	CHEMBL297453	NA	DB12116
Gamma-tocopherol	NA	Caenorhabditis elegans	fem-1(hc17)	20 ug/ml	17	NA	NA	NA	17169403	NA	NA	CHEMBL2151591	NA	NA
4-dafachronic acid	NA	Caenorhabditis elegans	N2	250 nM	0	2.6	NA	NA	17360327	NA	NA	CHEMBL1232254, CHEMBL2387006	42628074, 16734910	NA
Rhodiola rosea	NA	Drosophila melanogaster	NA	30 mg/mL	11.9	NA	Female	NA	17990971	Mix	NA	NA	NA	NA
Hydrogen Sulphide	NA	Caenorhabditis elegans	N2	50ppm	74	NA	NA	NA	18077331	NA	NA	CHEMBL1200739	NA	NA
Acticoa powder	Cocoa polyphenolic extract	Rattus norvegicus	Wistar-Unilever	24 mg/5 ml/kg	11	NA	NA	NA	18179729	Mix	NA	NA	NA	NA
FCCP	Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone	Caenorhabditis elegans	N2	NA	28	21.4	NA	NA	18221415	NA	NA	CHEMBL457504	NA	NA
Rhodiola rosea root extract	NA	Caenorhabditis elegans	N2	10 µg/ml	15	NA	NA	NA	18536978	Mix	NA	NA	NA	NA
SkQ1	10-(6'-plastoquinonyl) decyltriphenylphosphonium	Drosophila melanogaster	NA	20pM-20nM	114	NA	Female	NA	19120018	NA	NA	NA	16679091	NA
Pine Bark extract	NA	Caenorhabditis elegans	N2	10 µg/mL	NA	5.2	NA	NA	19350411	Mix	NA	NA	NA	NA
Psoralea corylifolia extract	NA	Caenorhabditis elegans	N2	10 µg/mL	NA	9.8	NA	NA	19350411	Mix	NA	NA	NA	NA
Carbonylcyanide-3-chlorophenylhydrazone	CCCP	Caenorhabditis elegans	N2	10µm	60	NA	NA	NA	19442682	NA	NA	CHEMBL224214	2603	NA
Black tea extract	NA	Drosophila melanogaster	NA	10 mg/ml	10	NA	NA	NA	19770032	Mix	NA	NA	NA	NA
Reishi polysaccharide	Ganoderma lucidum polysaccharide	Caenorhabditis elegans	N2	100 ppm	35	NA	NA	NA	19837596	Mix	NA	NA	NA	NA
SQDB	Shi Quan Da Bu Tang Herbal Formula	Caenorhabditis elegans	N2	100 µg/ml	12	NA	NA	NA	20179756	Mix	NA	NA	NA	NA
VI-28	NA	Mus musculus	C57BL/6J	0.005	7.2	NA	Female	NS	20370440	Mix	NA	NA	NA	NA
Indolepropionamide	IPAM	Philodina acuticornis	odiosa	10 µM	137.8	NA	NA	NA	20421998	NA	NA	NA	21703095	NA
Phaseolus vulgaris Extract	NA	Caenorhabditis elegans	N2	150 µg / mL	13.2	NA	NA	NA	20455573	Mix	NA	NA	NA	NA
Marine collagen peptides	MCPs	Rattus norvegicus	Sprague-Dawley	0.09	11	13	NA	NA	20553190	Mix	NA	NA	NA	NA
S,S-trolox-carnosine	STC	Drosophila melanogaster	NA	50 mg/L	16	NA	Male	NA	20681748	NA	NA	NA	129843828	NA
Procyanidins	NA	Caenorhabditis elegans	N2	65 µg/ml	12.1	NA	NA	NA	20717869	NA	NA	NA	107876	NA
Stachys lavandulifolia ethanol extract	NA	Drosophila melanogaster	Oregon R	4 ul/100 ml media	12.4	6.4	Male	NA	20738162	Mix	NA	NA	NA	NA
Stachys lavandulifolia water extract	NA	Drosophila melanogaster	Oregon R	12 ul/100 ml media	21.9	8	Female	NA	20738162	Mix	NA	NA	NA	NA
Diallyl trisulfide	DATS	Caenorhabditis elegans	TJ1060	10 µM	13	NA	NA	NA	21296648	NA	NA	CHEMBL123040	NA	NA
Oregano and Cranberry extracts	NA	Anastrepha ludens	Loew	0.02	43	NA	NA	NA	21455602	Mix	NA	NA	NA	NA
Caffeic acid	NA	Caenorhabditis elegans	N2	300 µM	11	NA	NA	NA	21503726	NA	NA	CHEMBL145	NA	DB01880
Q3'G	quercetin 3'-O-beta-D-glucopyranoside	Caenorhabditis elegans	N2	21 µg/mL	12	NA	NA	NA	21563825	NA	NA	CHEMBL250450	5280804	DB12665
Q3M	3-O-beta-D-glucopyranoside-(4-1)-beta-D-glucopyranoside	Caenorhabditis elegans	N2	20 µg/mL	20	NA	NA	NA	21563825	Mix	NA	NA	NA	NA
Oxoline	NA	Caenorhabditis elegans	N2	1 mM	13	18	NA	NA	21765926	NA	NA	NA	169137	NA
Protease treated royal jelly	Royalactin	Caenorhabditis elegans	N2	10 µg/ml	18	44	NA	NA	21858156	Mix	NA	NA	NA	NA
Astragalus membranaceus polysaccharide	Astragalan	Caenorhabditis elegans	N2	1-2.5 mg/ml	23.8	NA	NA	NA	21892924	Mix	NA	NA	NA	NA
Rosa damascena extract	NA	Drosophila melanogaster	B	NA	22.4	12.7	Male	NA	21928072	Mix	NA	NA	NA	NA
Dafadine-A	NA	Caenorhabditis elegans	N2	50 µM	29	NA	NA	NA	22057127	NA	NA	CHEMBL1585869	NA	NA
SB203580	NA	Drosophila melanogaster	Oregon R	300 µM	30.3	NA	NA	NA	22363408	NA	NA	CHEMBL10	NA	NA
HA-1004	NA	Drosophila melanogaster	Oregon R	1-10 µM	18	NA	NA	NA	22363408	NA	NA	CHEMBL143054	NA	NA
Erbstatin analog	NA	Drosophila melanogaster	Oregon R	5 mM	18	NA	NA	NA	22363408	NA	NA	CHEMBL17329	NA	NA
PD-98059	NA	Drosophila melanogaster	Oregon R	300-1000 µM	27	NA	NA	NA	22363408	NA	NA	CHEMBL35482	NA	NA
PP2 AG1879	NA	Drosophila melanogaster	Oregon R	300 µM	22.8	NA	NA	NA	22363408	NA	NA	CHEMBL406845	NA	NA
Tyrphostin AG 1295	NA	Drosophila melanogaster	Oregon R	300-500 µM	22.5	NA	NA	NA	22363408	NA	NA	CHEMBL7724	2048	NA
Tyrphostin AG 1478	NA	Drosophila melanogaster	Oregon R	100 µM	19.5	NA	NA	NA	22363408	NA	NA	CHEMBL7917	2051	NA
Damnacanthus officinarum leaf extract	NA	Caenorhabditis elegans	N2	1200 µg/mL	18.6	NA	NA	NA	22370553	Mix	NA	NA	NA	NA
Medium-chain triglyceride oil	NA	Mus musculus	UM-HET3	60000mg/kg of diet	-1.1	NA	Male	NS	22451473	Mix	NA	NA	NA	NA
1,2,4-triazolo[1,5-a]pyridine	NA	Caenorhabditis elegans	N2	500 nM	12	NA	NA	NA	22509764	NA	NA	NA	67508	NA
HuminFeed	NA	Caenorhabditis elegans	N2	400 µM	12.5	NA	NA	NA	22529848	Mix	NA	NA	NA	NA
D-chiro-inositol	NA	Drosophila melanogaster	Canton S	NA	16.6	NA	Male	NA	22843669	NA	NA	CHEMBL1222251, CHEMBL1231671, CHEMBL1950780, CHEMBL3976780	892	DB03106, DB13178
Cynomorium songaricum Rupr.	Suoyang	Drosophila melanogaster	Canton S	10 mg/ml	1.5	NA	Male	NS	22844336	Mix	NA	NA	NA	NA
Black rice extract	NA	Drosophila melanogaster	Oregon R	30 mg/ml	14	NA	NA	NA	22930061	Mix	NA	NA	NA	NA
Apple flesh	NA	Saccharomyces cerevisiae	MCY4/KlLSM4::kanMX4	1 gr	7	NA	NA	NS	22970337	Mix	NA	NA	NA	NA
4-hydroxy-E-globularinin	NA	Caenorhabditis elegans	N2	200 uM	6.4	NA	NA	NA	23000058	ID's Not Found	NA	NA	NA	NA
Nolinospiroside F	NA	Saccharomyces cerevisiae	K6001	10 µM	21.3	NA	NA	NA	23439553	NA	NA	NA	21630160	NA
Malate	NA	Caenorhabditis elegans	N2	10 mM	14	NA	NA	NA	23472183	NA	NA	CHEMBL1455497	NA	DB12751
Ascr#2	hydroxy ketone ascaroside	Caenorhabditis elegans	N2	400 nM	14	NA	NA	NA	23509272	NA	NA	CHEMBL1221888	16066475	NA
Arsenite	NA	Caenorhabditis elegans	N2	100 nM	10	NA	NA	NA	23534459	NA	NA	CHEMBL1231071	NA	NA
Ethidium bromide	NA	Caenorhabditis elegans	N2	5 µg/ml	30.1	NA	NA	NA	23698443	NA	NA	CHEMBL284328	NA	NA
GYY4137	NA	Caenorhabditis elegans	N2	100 µM	0.4	NA	NA	NA	24093496	NA	NA	CHEMBL2158901	NA	NA
Acanthophora spicifera extract	Red Algae extract	Brachionus manjavacas	NA	5 µg/ml	14	NA	NA	NA	24120568	Mix	NA	NA	NA	NA
Peyssonnelia sp. extract	Red Algae extract	Brachionus manjavacas	NA	2 µg/ml	8.5	NA	NA	NA	24120568	Mix	NA	NA	NA	NA
LY-165,163	PAPP	Caenorhabditis elegans	NA	33 µM	33	NA	NA	NA	24134630	NA	NA	CHEMBL1256693	NA	NA
Doxycycline hydrochloride	NA	Caenorhabditis elegans	NA	33 µM	18	NA	NA	NA	24134630	NA	DOXYCYCLINE HYDROCHLORIDE	CHEMBL1256723	54685920	DBSALT000897
Psora-4	NA	Caenorhabditis elegans	NA	88 µM	42	NA	NA	NA	24134630	NA	NA	CHEMBL1256851	NA	NA
Trequinsin hydrochloride	NA	Caenorhabditis elegans	NA	88µM	27	NA	NA	NA	24134630	NA	TREQUINSIN HYDROCHLORIDE	CHEMBL1256910	3060974	NA
Cortexolone maleate	NA	Caenorhabditis elegans	NA	33µM	11	NA	NA	NA	24134630	NA	NA	CHEMBL1554717	NA	NA
AMN082	NA	Caenorhabditis elegans	NA	33 µM	8	NA	NA	NA	24134630	NA	NA	CHEMBL1613220	NA	NA
LFM-A13	NA	Caenorhabditis elegans	NA	88 µM	27	NA	NA	NA	24134630	NA	NA	CHEMBL228043	NA	NA
4-phenyl-3-furoxancarbonitrile	NA	Caenorhabditis elegans	NA	88 µM	30	NA	NA	NA	24134630	NA	NA	CHEMBL336467	NA	NA
Cis-(Z)-Flupenthixol dihydrochloride	NA	Caenorhabditis elegans	NA	33 µM	30	NA	NA	NA	24134630	NA	NA	CHEMBL54661	NA	NA
Dihydroergocristine methanesulfonate	NA	Caenorhabditis elegans	NA	176 µM	34	NA	NA	NA	24134630	NA	NA	CHEMBL601773	NA	NA
Octoclothepin maleate	(+/-)-Octoclothepin maleate	Caenorhabditis elegans	NA	13 µM	38	NA	NA	NA	24134630	NA	NA	CHEMBL64249	NA	NA
(R,R)-cis-Diethyl tetrahydro-2,8-chrysenediol	NA	Caenorhabditis elegans	NA	33 µM	7	NA	NA	NA	24134630	NA	NA	CHEMBL282489	446849	NA
BRL 50481	NA	Caenorhabditis elegans	NA	176 µM	18	NA	NA	NA	24134630	NA	NA	CHEMBL484928	2921148	NA
Hexahydro-sila-diphenidol	NA	Caenorhabditis elegans	NA	88 µM	15	NA	NA	NA	24134630	NA	NA	CHEMBL3545990	3602	NA
N-(2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamide	NA	Caenorhabditis elegans	NA	33 µM	35	NA	NA	NA	24134630	NA	NA	CHEMBL93403	3626837	NA
MPTP	NA	Caenorhabditis elegans	N2	10 nM	8	NA	Hermaphrodite	NA	24199155	NA	NA	CHEMBL24172	NA	NA
Korean red ginseng tonic	Panax ginseng	Drosophila melanogaster	w1118	12 µg/ml	13.5	NA	Female	NA	24265871	Mix	NA	NA	NA	NA
AU701	Apple pectine AU701	Drosophila melanogaster	Canton S	0.30%	1.2	NA	Male	NS	24305778	Mix	NA	NA	NA	NA
CU701	Citrus pectine CU703	Drosophila melanogaster	Canton S	0.30%	0	NA	Male	NS	24305778	Mix	NA	NA	NA	NA
Ludwigia octovalvis extract	NA	Drosophila melanogaster	Canton S	100 µg/ml	16.1	NA	Male	NA	24338263	Mix	NA	NA	NA	NA
Cranberry extract	NA	Caenorhabditis elegans	N2	2 mg/ml	12.8	NA	NA	NA	24566444	Mix	NA	NA	NA	NA
Shiquan dabu wan	SQ	Caenorhabditis elegans	N2	6.2 g/L	14.5	NA	NA	NA	24952637	Mix	NA	NA	NA	NA
Caffeic acid phenethylester	CAPE	Caenorhabditis elegans	NA	NA	9	17	NA	NA	24964141	NA	NA	CHEMBL319244	5281787	NA
Amla juice	Emblicaæofficinalis	Drosophila melanogaster	NA	20 ml	5.9	NA	NA	NA	24967413	Mix	NA	NA	NA	NA
Astragalus polysaccharide	NA	Caenorhabditis elegans	N2	50 µg/ml	7	NA	NA	NA	25186652	Mix	NA	NA	NA	NA
Bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)-decandioate	IAC	Aeolosoma viride	NA	2.5 uM	98.6	NA	NA	NA	25190068	NA	NA	NA	11272241	NA
Mulberry leaf polyphenols	NA	Caenorhabditis elegans	N2	25 mg/mL	22.5	NA	NA	NA	25323576	Mix	NA	NA	NA	NA
Acanthopanax sessiliflorus stem extract	NA	Caenorhabditis elegans	N2	500 mg/L	18	20	NA	NA	25324932	Mix	NA	NA	NA	NA
Royalactin	NA	Caenorhabditis elegans	N2	0.04 ug/ml	26.8	NA	NA	NA	25456847	Mix	NA	NA	NA	NA
Cinnamon Extract	NA	Drosophila melanogaster	w1118	75 mg/ml	37	NA	Female	NA	25456850	Mix	NA	NA	NA	NA
Proanthocyanidins from Kunlun Chrysanthemum flowers	NA	Drosophila melanogaster	Oregon R+	NA	15.5	10.4	Female	NA	25628774	Mix	NA	NA	NA	NA
N-acetyl-l-histidine	NA	Caenorhabditis elegans	N2	100 µM	3	NA	NA	NS	25643626	NA	NA	CHEMBL3251664	NA	NA
Caprylate	NA	Caenorhabditis elegans	N2	100 µM	1	NA	NA	NS	25643626	NA	NA	NA	119389	NA
DL-isocitrate	NA	Caenorhabditis elegans	N2	10 mM	-28	NA	NA	NA	25643626	NA	NA	NA	1198	NA
Ribose	NA	Caenorhabditis elegans	N2	1 mM	9	NA	NA	NA	25643626	NA	NA	CHEMBL1159662	10975657	NA
10-hydroxy-2-decenoic Acid	NA	Caenorhabditis elegans	N2	25 µM	10	14	NA	NA	25789174	NA	NA	NA	5312738	NA
Garlic extract	Allium sativum	Caenorhabditis elegans	N2	50 ppm	21	NA	NA	NA	25940980	Mix	NA	NA	NA	NA
Soybean trypsin inhibitor	NA	Caenorhabditis elegans	N2	5 uM	8.7	NA	NA	NA	25959406	Peptide	NA	NA	NA	NA
Dehydroabietic acid	NA	Caenorhabditis elegans	N2	50 µM	4.8	8.3	NA	NS	25976661	NA	NA	CHEMBL12850	NA	NA
Beta-Guanidinopropionic acid	NA	Drosophila melanogaster	w1118	900 mM	9.1	NA	Male	NA	26120775	NA	NA	CHEMBL20489	NA	NA
(Iso)lappaol A	NA	Caenorhabditis elegans	N2	100 uM	11.2	NA	NA	NA	26141518	NA	NA	NA	102232211	NA
Lappaol C	NA	Caenorhabditis elegans	N2	10 uM	11.3	NA	NA	NA	26141518	NA	NA	NA	323896	NA
Lappaol F	NA	Caenorhabditis elegans	N2	100 uM	12.5	NA	NA	NA	26141518	NA	NA	NA	73425459	NA
(R)-2-hydroxyglutarate	NA	Caenorhabditis elegans	NA	8 mM	42.9	NA	NA	NA	26190651	NA	NA	CHEMBL1614745	NA	NA
