xCell2

This is the development version of xCell2; to use it, please install the devel version of Bioconductor.

A Tool for Generic Cell Type Enrichment Analysis


Bioconductor version: Development (3.21)

xCell2 provides methods for cell type enrichment analysis using cell type signatures. It includes three main functions - 1. xCell2Train for training custom references objects from bulk or single-cell RNA-seq datasets. 2. xCell2Analysis for conducting the cell type enrichment analysis using the custom reference. 3. xCell2GetLineage for identifying dependencies between different cell types using ontology.

Author: Almog Angel [aut, cre] (ORCID: ), Dvir Aran [aut] (ORCID: )

Maintainer: Almog Angel <almog.angel at campus.technion.ac.il>

Citation (from within R, enter citation("xCell2")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("xCell2")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews DifferentialExpression, GeneExpression, GeneSetEnrichment, ImmunoOncology, Microarray, RNASeq, SingleCell, Software, Transcriptomics
Version 0.99.107
In Bioconductor since BioC 3.21 (R-4.5)
License GPL (>= 3)
Depends R (>= 4.0.0)
Imports SummarizedExperiment, SingleCellExperiment, Rfast, singscore, AnnotationHub, ontologyIndex, tibble, dplyr, BiocParallel, Matrix, minpack.lm, pracma, methods, readr, magrittr, progress, quadprog
System Requirements
URL https://github.com/AlmogAngel/xCell2
Bug Reports https://github.com/AlmogAngel/xCell2/issues
See More
Suggests testthat, knitr, rmarkdown, ggplot2, randomForest, tidyr, EnhancedVolcano
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64) xCell2_0.99.107.zip
macOS Binary (x86_64) xCell2_0.99.107.tgz
macOS Binary (arm64) xCell2_0.99.107.tgz
Source Repository git clone https://git.bioconductor.org/packages/xCell2
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/xCell2
Bioc Package Browser https://code.bioconductor.org/browse/xCell2/
Package Short Url https://bioconductor.org/packages/xCell2/
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