MetaboDynamics

This is the development version of MetaboDynamics; to use it, please install the devel version of Bioconductor.

Bayesian analysis of longitudinal metabolomics data


Bioconductor version: Development (3.21)

MetaboDynamics is an R-package that provides a framework of probabilistic models to analyze longitudinal metabolomics data. It enables robust estimation of mean concentrations despite varying spread between timepoints and reports differences between timepoints as well as metabolite specific dynamics profiles that can be used for identifying "dynamics clusters" of metabolites of similar dynamics. Provides probabilistic over-representation analysis and comparison betweeen clusters of different experimental conditions.

Author: Katja Danielzik [aut, cre] (ORCID: ), Simo Kitanovski [ctb], Johann Matschke [ctb], Daniel Hoffmann [ctb]

Maintainer: Katja Danielzik <katja.danielzik at uni-due.de>

Citation (from within R, enter citation("MetaboDynamics")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("MetaboDynamics")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MetaboDynamics")
1. MetaboDynamics HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Bayesian, FunctionalPrediction, KEGG, Metabolomics, MultipleComparison, Software
Version 0.99.18
In Bioconductor since BioC 3.21 (R-4.5)
License GPL (>= 3)
Depends R (>= 4.4.0)
Imports dplyr, ggplot2, KEGGREST, methods, Rcpp (>= 0.12.0), RcppParallel (>= 5.0.1), rstan (>= 2.18.1), rstantools (>= 2.4.0), S4Vectors, stringr, SummarizedExperiment, tidyr
System Requirements GNU make
URL https://github.com/KatjaDanielzik/MetaboDynamics
Bug Reports https://github.com/KatjaDanielzik/MetaboDynamics/issues
See More
Suggests knitr, rmarkdown, BiocStyle, testthat (>= 3.0.0)
Linking To BH (>= 1.66.0), Rcpp (>= 0.12.0), RcppEigen (>= 0.3.3.3.0), RcppParallel (>= 5.0.1), rstan (>= 2.18.1), StanHeaders (>= 2.18.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MetaboDynamics_0.99.18.tar.gz
Windows Binary (x86_64) MetaboDynamics_0.99.18.zip
macOS Binary (x86_64) MetaboDynamics_0.99.18.tgz
macOS Binary (arm64) MetaboDynamics_0.99.18.tgz
Source Repository git clone https://git.bioconductor.org/packages/MetaboDynamics
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/MetaboDynamics
Bioc Package Browser https://code.bioconductor.org/browse/MetaboDynamics/
Package Short Url https://bioconductor.org/packages/MetaboDynamics/
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