Package: aggregateBioVar
Type: Package
Title: Differential Gene Expression Analysis for Multi-subject
        scRNA-seq
Version: 1.23.0
Authors@R: c(
    person(given = "Jason", family = "Ratcliff",
        email = "jason-ratcliff@uiowa.edu", role = c("aut", "cre"),
        comment = c(ORCID = "0000-0001-7079-334X")),
    person(given = "Andrew", family = "Thurman", 
        email = "andrew.thurman2@gmail.com", role = "aut"),
    person(given = "Michael", family = "Chimenti", 
        email = "michael-chimenti@uiowa.edu", role = "ctb"),
    person(given = "Alejandro", family = "Pezzulo", 
        email = "alejandro-pezzulo@uiowa.edu", role = "ctb")
    )
URL: https://github.com/jasonratcliff/aggregateBioVar
BugReports: https://github.com/jasonratcliff/aggregateBioVar/issues
Description: For single cell RNA-seq data collected from more than one
        subject (e.g. biological sample or technical replicates), this
        package contains tools to summarize single cell gene expression
        profiles at the level of subject. A SingleCellExperiment object
        is taken as input and converted to a list of
        SummarizedExperiment objects, where each list element
        corresponds to an assigned cell type. The SummarizedExperiment
        objects contain aggregate gene-by-subject count matrices and
        inter-subject column metadata for individual subjects that can
        be processed using downstream bulk RNA-seq tools.
License: GPL-3
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.1
biocViews: Software, SingleCell, RNASeq, Transcriptomics,
        Transcription, GeneExpression, DifferentialExpression
Depends: R (>= 4.0)
Imports: stats, methods, S4Vectors, SummarizedExperiment,
        SingleCellExperiment, Matrix, tibble, rlang
Suggests: BiocStyle, magick, knitr, rmarkdown, testthat, BiocGenerics,
        DESeq2, magrittr, dplyr, ggplot2, cowplot, ggtext,
        RColorBrewer, pheatmap, viridis
Config/pak/sysreqs: zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:53:50 UTC
RemoteUrl: https://github.com/bioc/aggregateBioVar
RemoteRef: HEAD
RemoteSha: b5448dbe62f6e6b41d78d1f864567ffb7bea6798
NeedsCompilation: no
Packaged: 2026-05-29 08:50:05 UTC; root
Author: Jason Ratcliff [aut, cre] (ORCID:
    <https://orcid.org/0000-0001-7079-334X>),
  Andrew Thurman [aut],
  Michael Chimenti [ctb],
  Alejandro Pezzulo [ctb]
Maintainer: Jason Ratcliff <jason-ratcliff@uiowa.edu>
Built: R 4.6.0; ; 2026-05-29 08:51:57 UTC; windows
