Spatial cell-type inter-correlation by density in R


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Documentation for package ‘scider’ version 1.7.2

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allocateCells Annotate all cells with contour level of cell type-specific density.
cellsInRegion Check which cells are in which regions
computeDensity Perform kernel density estimation on SpatialExperiment
computeDensityHex Perform kernel density estimation on SpatialExperiment
contour2sf Draw a contour region on some density level
coord_hash Hash two 15-bytes signed integers into one 32-bytes integer.
corDensity Test for density correlation between two cell types.
findNbrsGrid Construct a neighbour list from grid coordinates.
findNbrsSNN Construct a SNN neighbour list from assay.
findNbrsSpatial Construct a distance-based neighbour list from cell coordinates.
findROI Find ROIs based on cell type-specific densities via graph-based method.
getClusters Cluster cells in spe using graph methods.
getContour Get contour from density
getContourRegions Calculate areas between every two density levels
getNiche Build a niche assay based on the profile of neighbouring cells
globalMoran Calculate global Moran for 1 to 2 variables.
grid2df Convert x,y nodes to data.frame of polygons
grid2sf Convert x,y nodes to sf polygons
gridDensity Perform kernel density estimation on SpatialExperiment for cell types of interest
gridSPE Summarize a SpatialExperiment object at grid-level
localMoran Calculate local Moran for 1 to 2 variables.
mergeROI Manually merge ROIs
normalizeAssay Perform log normalization for counts
plotCellCompo Plot cell type composition in each density level of cell of interest.
plotContour Plot contour lines.
plotContourRegion Visualising an sf object (for internal use only at the moment)
plotCorHeatmap Plot model statistics using heatmap.
plotDensCor Plot density correlation between two cell types
plotDensity Plot grid-based density.
plotDR Plot reduced dimensions.
plotGrid Plot grid from metadata.
plotImage Plot background image of spe
plotLISA Plotting LISA (e.g. moran)
plotPCA Plot reduced dimensions.
plotROI Plot ROIs on spatial.
plotSpatial Plot cells based on spatial coordinates.
plotUMAP Plot reduced dimensions.
postSelRegion Merge sel_region from the selectRegion function to SpatialExperiment.
realignVisium Scale and straighten out Visium coordinates
realignVisiumHD Scale and straighten out VisiumHD coordinates
runPCA Fast PCA using irlba.
runUMAP UMAP using uwot. Parameters are set to be similar to Seurat's
selectRegion Select region of interest from plot
spe2PB Given a 'SpatialExperiment' data object, create pseudo-bulk samples using the colData information and return a DGEList object
update_bound Update the x,y limits of a plot
[-method Subset for grid level analysis