RHTSLIB_LIBS=$(shell "${R_HOME}/bin${R_ARCH_BIN}/Rscript" -e \
    'Rhtslib::pkgconfig("PKG_LIBS")')
RHTSLIB_CPPFLAGS=$(shell "${R_HOME}/bin${R_ARCH_BIN}/Rscript" -e \
    'Rhtslib::pkgconfig("PKG_CPPFLAGS")')
PKG_LIBS=$(RHTSLIB_LIBS)
PKG_CPPFLAGS=$(RHTSLIB_CPPFLAGS)
#PKG_CPPFLAGS=-I "/Library/Developer/CommandLineTools/SDKs/MacOSX.sdk/usr/include/"
#https://github.com/Rdatatable/data.table/issues/4907#issuecomment-806131096 Makevars for macOS big sur
