Bioconductor 3.22 Released

diffHic

This is the development version of diffHic; for the stable release version, see diffHic.

Differential Analysis of Hi-C Data


Bioconductor version: Development (3.23)

Detects differential interactions across biological conditions in a Hi-C experiment. Methods are provided for read alignment and data pre-processing into interaction counts. Statistical analysis is based on edgeR and supports normalization and filtering. Several visualization options are also available.

Author: Aaron Lun, Gordon Smyth

Maintainer: Aaron Lun <infinite.monkeys.with.keyboards at gmail.com>, Gordon Smyth <smyth at wehi.edu.au>, Hannah Coughlin <coughlin.h at wehi.edu.au>

Citation (from within R, enter citation("diffHic")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("diffHic")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews Alignment, Clustering, Coverage, HiC, MultipleComparison, Normalization, Preprocessing, Sequencing, Software
Version 1.43.0
In Bioconductor since BioC 3.1 (R-3.2) (10.5 years)
License GPL-3
Depends R (>= 3.5), GenomicRanges, InteractionSet, SummarizedExperiment
Imports Rsamtools, Rhtslib, Biostrings, BSgenome, rhdf5, edgeR, limma, csaw, locfit, methods, IRanges, S4Vectors, GenomeInfoDb, BiocGenerics, grDevices, graphics, stats, utils, Rcpp, rtracklayer
System Requirements C++, GNU make
URL
See More
Suggests BSgenome.Ecoli.NCBI.20080805, Matrix, testthat
Linking To Rhtslib(>= 1.13.1), Rcpp
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/diffHic
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/diffHic
Package Short Url https://bioconductor.org/packages/diffHic/
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