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This is the development version of dStruct; for the stable release version, see dStruct.

Identifying differentially reactive regions from RNA structurome profiling data

Bioconductor version: Development (3.20)

dStruct identifies differentially reactive regions from RNA structurome profiling data. dStruct is compatible with a broad range of structurome profiling technologies, e.g., SHAPE-MaP, DMS-MaPseq, Structure-Seq, SHAPE-Seq, etc. See Choudhary et al., Genome Biology, 2019 for the underlying method.

Author: Krishna Choudhary [aut, cre] , Sharon Aviran [aut]

Maintainer: Krishna Choudhary <kchoudhary at>

Citation (from within R, enter citation("dStruct")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Differential RNA structurome analysis using `dStruct` HTML R Script
Reference Manual PDF


biocViews Sequencing, Software, StatisticalMethod, StructuralPrediction
Version 1.11.0
In Bioconductor since BioC 3.14 (R-4.1) (2.5 years)
License GPL (>= 2)
Depends R (>= 4.1)
Imports zoo, ggplot2, purrr, reshape2, parallel, IRanges, S4Vectors, rlang, grDevices, stats, utils
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