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This package is for version 3.20 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see SANTA.

Spatial Analysis of Network Associations

Bioconductor version: Development (3.20)

This package provides methods for measuring the strength of association between a network and a phenotype. It does this by measuring clustering of the phenotype across the network (Knet). Vertices can also be individually ranked by their strength of association with high-weight vertices (Knode).

Author: Alex Cornish [cre, aut]

Maintainer: Alex Cornish <alexcornish88 at>

Citation (from within R, enter citation("SANTA")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Introduction to SANTA HTML R Script
Reference Manual PDF


biocViews Clustering, Network, NetworkEnrichment, Software
Version 2.41.2
In Bioconductor since BioC 2.12 (R-3.0) (11 years)
License GPL (>= 2)
Depends R (>= 4.1), igraph
Imports graphics, Matrix, methods, stats
System Requirements
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Suggests BiocGenerics, BioNet, formatR, knitr, msm, org.Sc.sgd.db, markdown, rmarkdown, RUnit
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Follow Installation instructions to use this package in your R session.

Source Package SANTA_2.41.2.tar.gz
Windows Binary
macOS Binary (x86_64) SANTA_2.41.2.tgz
macOS Binary (arm64) SANTA_2.41.2.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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