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This is the development version of HiTC; for the stable release version, see HiTC.

High Throughput Chromosome Conformation Capture analysis

Bioconductor version: Development (3.20)

The HiTC package was developed to explore high-throughput 'C' data such as 5C or Hi-C. Dedicated R classes as well as standard methods for quality controls, normalization, visualization, and further analysis are also provided.

Author: Nicolas Servant

Maintainer: Nicolas Servant <nicolas.servant at>

Citation (from within R, enter citation("HiTC")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Hi-C data analysis using HiTC PDF R Script
Introduction to HiTC package PDF R Script
Reference Manual PDF


biocViews HiC, HighThroughputSequencing, Sequencing, Software
Version 1.49.0
In Bioconductor since BioC 2.10 (R-2.15) (12 years)
License Artistic-2.0
Depends R (>= 2.15.0), methods, IRanges, GenomicRanges
Imports Biostrings, graphics, grDevices, rtracklayer, RColorBrewer, Matrix, parallel, GenomeInfoDb
System Requirements
See More
Suggests BiocStyle, HiCDataHumanIMR90, BSgenome.Hsapiens.UCSC.hg18
Linking To
Depends On Me
Imports Me
Suggests Me HiCDCPlus, HiCDataHumanIMR90, adjclust
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package HiTC_1.49.0.tar.gz
Windows Binary
macOS Binary (x86_64) HiTC_1.49.0.tgz
macOS Binary (arm64) HiTC_1.49.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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