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This is the development version of HELP; for the stable release version, see HELP.

Tools for HELP data analysis

Bioconductor version: Development (3.20)

The package contains a modular pipeline for analysis of HELP microarray data, and includes graphical and mathematical tools with more general applications.

Author: Reid F. Thompson <reid.thompson at>, John M. Greally <john.greally at>, with contributions from Mark Reimers <mreimers at>

Maintainer: Reid F. Thompson <reid.thompson at>

Citation (from within R, enter citation("HELP")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

1. Primer PDF R Script
Reference Manual PDF


biocViews CpGIsland, DNAMethylation, DataImport, Microarray, Preprocessing, QualityControl, Software, TwoChannel, Visualization
Version 1.63.0
In Bioconductor since BioC 2.3 (R-2.8) (15.5 years)
License GPL (>= 2)
Depends R (>= 2.8.0), stats, graphics, grDevices, Biobase, methods
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Follow Installation instructions to use this package in your R session.

Source Package HELP_1.63.0.tar.gz
Windows Binary
macOS Binary (x86_64) HELP_1.63.0.tgz
macOS Binary (arm64) HELP_1.63.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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