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This is the development version of GladiaTOX; for the stable release version, see GladiaTOX.

R Package for Processing High Content Screening data

Bioconductor version: Development (3.20)

GladiaTOX R package is an open-source, flexible solution to high-content screening data processing and reporting in biomedical research. GladiaTOX takes advantage of the tcpl core functionalities and provides a number of extensions: it provides a web-service solution to fetch raw data; it computes severity scores and exports ToxPi formatted files; furthermore it contains a suite of functionalities to generate pdf reports for quality control and data processing.

Author: Vincenzo Belcastro [aut, cre], Dayne L Filer [aut], Stephane Cano [aut]

Maintainer: PMP S.A. R Support <DL.RSupport at>

Citation (from within R, enter citation("GladiaTOX")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

GladiaTOX HTML R Script
Reference Manual PDF


biocViews Normalization, Preprocessing, QualityControl, Software, WorkflowStep
Version 1.21.0
In Bioconductor since BioC 3.9 (R-3.6) (5 years)
License GPL-2
Depends R (>= 3.6.0), data.table (>= 1.9.4)
Imports DBI, RMariaDB, RSQLite, numDeriv, RColorBrewer, parallel, stats, methods, graphics, grDevices, xtable, tools, brew, stringr, RJSONIO, ggplot2, ggrepel, tidyr, utils, RCurl, XML
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Suggests roxygen2, knitr, rmarkdown, testthat, BiocStyle
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Follow Installation instructions to use this package in your R session.

Source Package GladiaTOX_1.21.0.tar.gz
Windows Binary
macOS Binary (x86_64) GladiaTOX_1.21.0.tgz
macOS Binary (arm64) GladiaTOX_1.21.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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