Registration Open for Bioc2024
Early registration discount pricing ends May 31!


This is the development version of DegNorm; for the stable release version, see DegNorm.

DegNorm: degradation normalization for RNA-seq data

Bioconductor version: Development (3.20)

This package performs degradation normalization in bulk RNA-seq data to improve differential expression analysis accuracy.

Author: Bin Xiong and Ji-Ping Wang

Maintainer: Ji-Ping Wang <jzwang at>

Citation (from within R, enter citation("DegNorm")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

DegNorm HTML R Script
Reference Manual PDF


biocViews Alignment, BatchEffect, Coverage, DataImport, DifferentialExpression, GeneExpression, ImmunoOncology, Normalization, QualityControl, RNASeq, Sequencing, Software
Version 1.15.0
In Bioconductor since BioC 3.12 (R-4.0) (3.5 years)
License LGPL (>= 3)
Depends R (>= 4.0.0), methods
Imports Rcpp (>= 1.0.2), GenomicFeatures, txdbmaker, parallel, foreach, S4Vectors, doParallel, Rsamtools(>= 1.31.2), GenomicAlignments, heatmaply, data.table, stats, ggplot2, GenomicRanges, IRanges, plyr, plotly, utils, viridis
System Requirements
Bug Reports
See More
Suggests knitr, rmarkdown, formatR
Linking To Rcpp, RcppArmadillo, S4Vectors, IRanges
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DegNorm_1.15.0.tar.gz
Windows Binary (64-bit only)
macOS Binary (x86_64) DegNorm_1.15.0.tgz
macOS Binary (arm64) DegNorm_1.15.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
Bioc Package Browser
Package Short Url
Package Downloads Report Download Stats