Bioconductor 3.22 Released

BreastSubtypeR

This is the development version of BreastSubtypeR; for the stable release version, see BreastSubtypeR.

Cohort-aware methods for intrinsic molecular subtyping of breast cancer


Bioconductor version: Development (3.23)

BreastSubtypeR provides an assumption-aware, multi-method framework for intrinsic molecular subtyping of breast cancer. The package harmonizes several published nearest-centroid (NC) and single-sample predictor (SSP) classifiers, supplies method-specific preprocessing and robust probe-to-gene mapping, and implements a cohort-aware AUTO mode that selectively enables classifiers compatible with the cohort composition. A local Shiny app (iBreastSubtypeR) is included for interactive analyses and to support users without programming experience.

Author: Qiao Yang [aut, cre] ORCID iD ORCID: 0000-0002-4098-3246 , Emmanouil G. Sifakis [aut] ORCID iD ORCID: 0000-0001-9919-4471

Maintainer: Qiao Yang <yq.kiuo at gmail.com>

Citation (from within R, enter citation("BreastSubtypeR")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("BreastSubtypeR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews Classification, GeneExpression, Preprocessing, RNASeq, Software, Visualization
Version 1.3.0
In Bioconductor since BioC 3.21 (R-4.5) (0.5 years)
License GPL-3
Depends R (>= 4.5.0)
Imports methods, Biobase, tidyselect, dplyr, ggplot2, magrittr, rlang, stringr, withr, edgeR, ComplexHeatmap, impute(>= 1.80.0), data.table (>= 1.16.0), RColorBrewer (>= 1.1-3), circlize (>= 0.4.16), ggrepel (>= 0.9.6), e1071 (>= 1.7-8), SummarizedExperiment, utils
System Requirements
URL https://doi.org/10.18129/B9.bioc.BreastSubtypeR https://github.com/yqkiuo/BreastSubtypeR https://github.com/JohanHartmanGroupBioteam/BreastSubtypeR
Bug Reports https://github.com/yqkiuo/BreastSubtypeR/issues
See More
Suggests lifecycle, tidyverse, shiny (>= 1.9.1), bslib (>= 0.8.0), BiocStyle, knitr, rmarkdown, testthat
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/BreastSubtypeR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/BreastSubtypeR
Package Short Url https://bioconductor.org/packages/BreastSubtypeR/
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