| adt_quality_control | Quality control for ADT count data |
| aggregateAcrossCells | Aggregate expression across cells |
| aggregateAcrossCells.se | Aggregate expression across cells in a SummarizedExperiment |
| aggregateAcrossGenes | Aggregate expression across genes |
| aggregateAcrossGenes.se | Aggregate expression across gene sets in a SummarizedExperiment |
| aggregateColData | Aggregate expression across cells in a SummarizedExperiment |
| analyze | Analyze single-cell data |
| analyze.se | Analyze single-cell data from a SummarizedExperiment |
| buildSnnGraph | Build a shared nearest neighbor graph |
| centerSizeFactors | Center size factors |
| chooseHighlyVariableGenes | Choose highly variable genes |
| choosePseudoCount | Choose a suitable pseudo-count |
| chooseRnaHvgs.se | Choose highly variable genes from a SummarizedExperiment |
| clusterGraph | Graph-based clustering of cells |
| clusterGraph.se | Graph-based clustering of cells in a SingleCellExperiment |
| clusterKmeans | K-means clustering |
| clusterKmeans.se | k-means clustering of cells in a SingleCellExperiment |
| combineFactors | Combine multiple factors |
| computeAdtQcMetrics | Quality control for ADT count data |
| computeBlockWeights | Compute block weights |
| computeClrm1Factors | Compute size factors for ADT counts |
| computeCrisprQcMetrics | Quality control for CRISPR count data |
| computeRnaQcMetrics | Quality control for RNA count data |
| computeRnaQcMetricsWithAltExps | Quick quality control for RNA data in a SummarizedExperiment |
| convertAnalyzeResults | Convert analysis results into a SingleCellExperiment |
| correctMnn | Batch correction with mutual nearest neighbors |
| correctMnn.se | MNN correction on a SingleCellExperiment |
| countGroupsByBlock | Count cells in groups and blocks |
| crispr_quality_control | Quality control for CRISPR count data |
| DelayedArray-method | Delayed log-normalization of a matrix |
| dim-method | Delayed log-normalization of a matrix |
| dimnames-method | Delayed log-normalization of a matrix |
| extract_array-method | Delayed log-normalization of a matrix |
| extract_sparse_array-method | Delayed log-normalization of a matrix |
| filterAdtQcMetrics | Quality control for ADT count data |
| filterCrisprQcMetrics | Quality control for CRISPR count data |
| filterRnaQcMetrics | Quality control for RNA count data |
| fitVarianceTrend | Fit a mean-variance trend |
| formatComputeAdtQcMetricsResult | Quick quality control for ADT data in a SummarizedExperiment |
| formatComputeCrisprQcMetricsResult | Quick quality control for CRISPR data in a SummarizedExperiment |
| formatComputeRnaQcMetricsResult | Quick quality control for RNA data in a SummarizedExperiment |
| formatModelGeneVariancesResult | Choose highly variable genes from a SummarizedExperiment |
| formatScoreMarkersResult | Score marker genes in a SummarizedExperiment |
| getTestAdtData.se | Get datasets for testing |
| getTestCrisprData.se | Get datasets for testing |
| getTestData.se | Get datasets for testing |
| getTestRnaData.se | Get datasets for testing |
| initializeCpp-method | Delayed log-normalization of a matrix |
| is_sparse-method | Delayed log-normalization of a matrix |
| LogNormalizedMatrix | Delayed log-normalization of a matrix |
| LogNormalizedMatrix-class | Delayed log-normalization of a matrix |
| LogNormalizedMatrixSeed | Delayed log-normalization of a matrix |
| LogNormalizedMatrixSeed-class | Delayed log-normalization of a matrix |
| matrixClass-method | Delayed log-normalization of a matrix |
| modelGeneVariances | Model per-gene variances in expression |
| normalizeAdtCounts.se | Normalize ADT counts in a SummarizedExperiment |
| normalizeCounts | Normalize the count matrix |
| normalizeCrisprCounts.se | Normalize CRISPR counts in a SummarizedExperiment |
| normalizeRnaCounts.se | Normalize RNA counts in a SummarizedExperiment |
| previewMarkers | Score marker genes in a SummarizedExperiment |
| quickAdtQc.se | Quick quality control for ADT data in a SummarizedExperiment |
| quickCrisprQc.se | Quick quality control for CRISPR data in a SummarizedExperiment |
| quickRnaQc.se | Quick quality control for RNA data in a SummarizedExperiment |
| reportGroupMarkerStatistics | Report marker statistics for a single group |
| rna_quality_control | Quality control for RNA count data |
| runAllNeighborSteps | Run all neighbor-related steps |
| runAllNeighborSteps.se | Run all nearest neighbor steps on a SummarizedExperiment |
| runPca | Principal components analysis |
| runPca.se | Principal components analysis of a Summarizedexperiment |
| runTsne | t-stochastic neighbor embedding |
| runTsne.se | t-SNE on a SummarizedExperiment |
| runUmap | Uniform manifold approxation and projection |
| runUmap.se | UMAP on a SummarizedExperiment |
| sanitizeSizeFactors | Sanitize size factors |
| scaleByNeighbors | Scale and combine multiple embeddings |
| scaleByNeighbors.se | Scale and combine multiple embeddings in a SingleCellExperiment |
| scoreGeneSet | Score gene set activity for each cell |
| scoreGeneSet.se | Score a gene set in a SummarizedExperiment |
| scoreMarkers | Score marker genes |
| scoreMarkers.se | Score marker genes in a SummarizedExperiment |
| subsampleByNeighbors | Subsample cells based on their neighbors |
| suggestAdtQcThresholds | Quality control for ADT count data |
| suggestCrisprQcThresholds | Quality control for CRISPR count data |
| suggestRnaQcThresholds | Quality control for RNA count data |
| summarizeEffects | Summarize pairwise effect sizes for each group |
| testEnrichment | Test for gene set enrichment |
| tsnePerplexityToNeighbors | t-stochastic neighbor embedding |
| type-method | Delayed log-normalization of a matrix |