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transmogR

This is the released version of transmogR; for the devel version, see transmogR.

Modify a set of reference sequences using a set of variants


Bioconductor version: Release (3.23)

transmogR provides the tools needed to crate a new reference genome or reference transcriptome, using a set of variants. Variants can be any combination of SNPs, Insertions and Deletions. The intended use-case is to enable creation of variant-modified reference transcriptomes for incorporation into transcriptomic pseudo-alignment workflows, such as salmon.

Author: Stevie Pederson [aut, cre] ORCID iD ORCID: 0000-0001-8197-3303

Maintainer: Stevie Pederson <stephen.pederson.au at gmail.com>

Citation (from within R, enter citation("transmogR")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("transmogR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("transmogR")
Creating a Variant-Modified Reference HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Alignment, GenomicVariation, Sequencing, Software, TranscriptomeVariant, VariantAnnotation
Version 1.8.1
In Bioconductor since BioC 3.19 (R-4.4) (2.5 years)
License GPL-3
Depends R (>= 4.1.0), Biostrings, GenomicRanges
Imports BSgenome, data.table, Seqinfo, GenomicFeatures, ggplot2 (>= 4.0.0), IRanges, jsonlite, matrixStats, methods, parallel, patchwork, scales, stats, S4Vectors, SummarizedExperiment, VariantAnnotation
System Requirements
URL https://github.com/smped/transmogR
Bug Reports https://github.com/smped/transmogR/issues
See More
Suggests BiocStyle, BSgenome.Hsapiens.UCSC.hg38, edgeR, extraChIPs, InteractionSet, knitr, readr, rmarkdown, rtracklayer, SimpleUpset, testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
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Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package transmogR_1.8.1.tar.gz
Windows Binary (x86_64) transmogR_1.8.1.zip
macOS Binary (big-sur-x86_64) transmogR_1.8.1.tgz
macOS Binary (sonoma-arm64) transmogR_1.8.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/transmogR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/transmogR
Bioc Package Browser https://code.bioconductor.org/browse/transmogR/
Package Short Url https://bioconductor.org/packages/transmogR/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.23 Source Archive