srnadiff
This is the released version of srnadiff; for the devel version, see srnadiff.
Finding differentially expressed unannotated genomic regions from RNA-seq data
Bioconductor version: Release (3.23)
srnadiff is a package that finds differently expressed regions from RNA-seq data at base-resolution level without relying on existing annotation. To do so, the package implements the identify-then-annotate methodology that builds on the idea of combining two pipelines approachs differential expressed regions detection and differential expression quantification. It reads BAM files as input, and outputs a list differentially regions, together with the adjusted p-values.
Author: Zytnicki Matthias [aut, cre], Gonzalez Ignacio [aut]
Maintainer: Zytnicki Matthias <matthias.zytnicki at inra.fr>
citation("srnadiff")):
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.
Installation
To install this package, start R (version "4.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("srnadiff")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("srnadiff")| The srnadiff package | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | Coverage, DifferentialExpression, Epigenetics, GeneExpression, ImmunoOncology, Preprocessing, SmallRNA, Software, StatisticalMethod |
| Version | 1.32.0 |
| In Bioconductor since | BioC 3.7 (R-3.5) (8.5 years) |
| License | GPL-3 |
| Depends | R (>= 3.6) |
| Imports | Rcpp (>= 0.12.8), stats, methods, S4Vectors, Seqinfo, rtracklayer, SummarizedExperiment, IRanges, GenomicRanges, DESeq2, edgeR, Rsamtools, GenomicFeatures, GenomicAlignments, grDevices, Gviz, BiocParallel, BiocManager, BiocStyle |
| System Requirements | C++11 |
| URL |
See More
| Suggests | knitr, rmarkdown, testthat, BiocManager, BiocStyle |
| Linking To | Rcpp |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | srnadiff_1.32.0.tar.gz |
| Windows Binary (x86_64) | srnadiff_1.32.0.zip (64-bit only) |
| macOS Binary (big-sur-x86_64) | srnadiff_1.32.0.tgz |
| macOS Binary (sonoma-arm64) | srnadiff_1.32.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/srnadiff |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/srnadiff |
| Bioc Package Browser | https://code.bioconductor.org/browse/srnadiff/ |
| Package Short Url | https://bioconductor.org/packages/srnadiff/ |
| Package Downloads Report | Download Stats |