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The Discordant Method: A Novel Approach for Differential Correlation

Bioconductor version: Release (3.19)

Discordant is an R package that identifies pairs of features that correlate differently between phenotypic groups, with application to -omics data sets. Discordant uses a mixture model that “bins” molecular feature pairs based on their type of coexpression or coabbundance. Algorithm is explained further in "Differential Correlation for Sequencing Data"" (Siska et al. 2016).

Author: Charlotte Siska [aut], McGrath Max [aut, cre], Katerina Kechris [aut, cph, ths]

Maintainer: McGrath Max <max.mcgrath at>

Citation (from within R, enter citation("discordant")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

The discordant R Package: A Novel Approach to Differential Correlation HTML R Script
Reference Manual PDF


biocViews BiologicalQuestion, Genetics, ImmunoOncology, Microarray, RNASeq, Software, StatisticalMethod, mRNAMicroarray
Version 1.28.0
In Bioconductor since BioC 3.5 (R-3.4) (7 years)
License GPL-3
Depends R (>= 4.1.0)
Imports Rcpp, Biobase, stats, biwt, gtools, MASS, tools, dplyr, methods, utils
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Suggests BiocStyle, knitr, testthat (>= 3.0.0)
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Follow Installation instructions to use this package in your R session.

Source Package discordant_1.28.0.tar.gz
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macOS Binary (x86_64) discordant_1.28.0.tgz
macOS Binary (arm64) discordant_1.28.0.tgz
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