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OVESEG-test to detect tissue/cell-specific markers

Bioconductor version: Release (3.19)

An R package for multiple-group comparison to detect tissue/cell-specific marker genes among subtypes. It provides functions to compute OVESEG-test statistics, derive component weights in the mixture null distribution model and estimate p-values from weightedly aggregated permutations. Obtained posterior probabilities of component null hypotheses can also portrait all kinds of upregulation patterns among subtypes.

Author: Lulu Chen <luluchen at>

Maintainer: Lulu Chen <luluchen at>

Citation (from within R, enter citation("OVESEG")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

OVESEG User Manual HTML R Script
Reference Manual PDF


biocViews CellBiology, GeneExpression, MultipleComparison, Software
Version 1.20.0
In Bioconductor since BioC 3.9 (R-3.6) (5 years)
License GPL-2
Depends R (>= 3.6)
Imports stats, utils, methods, BiocParallel, SummarizedExperiment, limma, fdrtool, Rcpp
System Requirements C++11
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Suggests knitr, rmarkdown, BiocStyle, testthat, ggplot2, gridExtra, grid, reshape2, scales
Linking To Rcpp
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Follow Installation instructions to use this package in your R session.

Source Package OVESEG_1.20.0.tar.gz
Windows Binary
macOS Binary (x86_64) OVESEG_1.20.0.tgz
macOS Binary (arm64) OVESEG_1.20.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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