MassArray

Analytical Tools for MassArray Data

Bioconductor version: Release (3.20)

This package is designed for the import, quality control, analysis, and visualization of methylation data generated using Sequenom's MassArray platform. The tools herein contain a highly detailed amplicon prediction for optimal assay design. Also included are quality control measures of data, such as primer dimer and bisulfite conversion efficiency estimation. Methylation data are calculated using the same algorithms contained in the EpiTyper software package. Additionally, automatic SNP-detection can be used to flag potentially confounded data from specific CG sites. Visualization includes barplots of methylation data as well as UCSC Genome Browser-compatible BED tracks. Multiple assays can be positionally combined for integrated analysis.

Author: Reid F. Thompson <reid.thompson at gmail.com>, John M. Greally <john.greally at einstein.yu.edu>

Maintainer: Reid F. Thompson <reid.thompson at gmail.com>

Citation (from within R, enter citation("MassArray")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MassArray")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MassArray")

1. Primer	PDF	R Script
Reference Manual	PDF

Need some help? Ask on the Bioconductor Support site!

Details

biocViews	DNAMethylation, DataImport, Genetics, ImmunoOncology, MassSpectrometry, SNP, Software, Visualization
Version	1.58.0
In Bioconductor since	BioC 2.6 (R-2.11) (14.5 years)
License	GPL (>=2)
Depends	R (>= 2.10.0), methods
Imports	graphics, grDevices, stats, utils
System Requirements
URL

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Build Report	Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	MassArray_1.58.0.tar.gz
Windows Binary (x86_64)	MassArray_1.58.0.zip (64-bit only)
macOS Binary (x86_64)	MassArray_1.58.0.tgz
macOS Binary (arm64)	MassArray_1.58.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/MassArray
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/MassArray
Bioc Package Browser	https://code.bioconductor.org/browse/MassArray/
Package Short Url	https://bioconductor.org/packages/MassArray/
Package Downloads Report	Download Stats