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BatchSVG

This is the released version of BatchSVG; for the devel version, see BatchSVG.

Identify Batch-Biased Spatially Variable Genes


Bioconductor version: Release (3.23)

BatchSVG is a method to identify batch-biased spatially variable genes (SVGs) in spatial transcriptomics data. The batch variable can be defined as sample, donor sex, or other batch effects of interest. The BatchSVG method is based on the binomial deviance model (Townes et al, 2019).

Author: Christine Hou [aut] ORCID iD ORCID: 0009-0001-5350-0629 , Kinnary Shah [aut, cre], Jacqueline R. Thompson [aut], Stephanie C. Hicks [aut, fnd] ORCID iD ORCID: 0000-0002-7858-0231

Maintainer: Kinnary Shah <kinnaryshahh at gmail.com>

Citation (from within R, enter citation("BatchSVG")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("BatchSVG")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BatchSVG")
Tutorial for spe object HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews BatchEffect, QualityControl, Software, Spatial, Transcriptomics
Version 1.4.0
In Bioconductor since BioC 3.21 (R-4.5) (1.5 years)
License Artistic-2.0
Depends R (>= 4.5.0)
Imports scry, dplyr, stats, rlang, cowplot, ggrepel, ggplot2, RColorBrewer, scales, SummarizedExperiment
System Requirements
URL https://github.com/christinehou11/BatchSVG https://christinehou11.github.io/BatchSVG
Bug Reports https://github.com/christinehou11/BatchSVG/issues
See More
Suggests testthat (>= 3.0.0), knitr, rmarkdown, BiocStyle, spatialLIBD
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BatchSVG_1.4.0.tar.gz
Windows Binary (x86_64) BatchSVG_1.4.0.zip
macOS Binary (big-sur-x86_64) BatchSVG_1.4.0.tgz
macOS Binary (sonoma-arm64) BatchSVG_1.4.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/BatchSVG
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/BatchSVG
Bioc Package Browser https://code.bioconductor.org/browse/BatchSVG/
Package Short Url https://bioconductor.org/packages/BatchSVG/
Package Downloads Report Download Stats